54536-23-1Relevant articles and documents
Trideuteromethylation Enabled by a Sulfoxonium Metathesis Reaction
Shen, Zuyuan,Zhang, Shilei,Geng, Huihui,Wang, Jiarui,Zhang, Xinyu,Zhou, Anqi,Yao, Cheng,Chen, Xiaobei,Wang, Wei
supporting information, p. 448 - 452 (2019/01/14)
A conceptually novel sulfoxonium metathesis reaction between TMSOI and cost-effective DMSO-d6 is developed for the efficient generation of a new trideuteromethylation reagent TDMSOI. The new reagent TDMSOI is produced highly efficiently by simply heating a mixture of TMSOI and DMSO-d6 and directly used for subsequent trideuteromethylation in a "one-pot" operation. The preparative power of the new versatile reagent and the "one-pot" protocol is demonstrated by its use to install the ?CD3 moiety into broad functionalities including phenols, thiophenols, acidic amines, and enolizable methylene units in high yield and at a useful level of deuteration (>87% D).
EPR and ENDOR spectroscopic study of the reactions of aromatic azides with gallium trichloride
Bencivenni, Giorgio,Cesari, Riccardo,Nanni, Daniele,El Mkami, Hassane,Walton, John C.
supporting information; experimental part, p. 5097 - 5104 (2010/12/24)
The reactions of gallium trichloride with phenyl and deuterio-phenyl azides, as well as with 4-methoxyphenyl azide and deuterium isotopomers, were examined by product analysis, CW EPR spectroscopy and pulsed ENDOR spectroscopy. The products included the corresponding anilines together with 4-aminodiphenylamine type dimers, and polyanilines. Complex CW EPR spectra of the radical cations of the dimers [ArNHC6H4NH 2]+ and trimers [ArNHC6H4NHC 6H4NH2]+ were obtained. These EPR spectra were analysed with the help of data from the deuterium-substituted analogues as well as the pulse Davies ENDOR spectra. DFT computations of the radical cations provided corroborating evidence and suggested the unpaired electrons were accommodated in extensive π-delocalised orbitals. A mechanism to account for the reductive conversion of aromatic azides to the corresponding anilines and thence to the dimers and trimers is proposed.
Synthesis of functionalized triazatriangulenes for application in photo- Switchable self-assembled monolayers
Kubitschke, Jens,Naether, Christian,Herges, Rainer
scheme or table, p. 5041 - 5055 (2010/11/05)
Various triazatriangulenes are synthesized by nucleophilic attack at the central C atom of triazatriangulenium ions. The molecular functions, especially azobenzenes, are fixed via an ethynyl linker by in situ deprotection of trimethylsilylalkynes. The structure of two of these molecules is further investigated by X-ray crystallography. The photo-inducedtrans/cis-isomerization of the azobenzene substituted derivatives is analyzed in solution and shows great promise for the preparation of switchable functionalized monolayers, as the triazatriangulenes are known for their self-assembly on gold surfaces. [1].
ISOTOPICALLY SUBSTITUTED PROTON PUMP INHIBITORS
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Page/Page column 27, (2008/06/13)
The invention relates to benzimidazoles of Formula (1) and to pharmaceutical compositions comprising these compounds, further to intermediates of Formula (2 and 3).
ON THE ESR IDENTIFICATION OF PARAMAGNETIC SPECIES OBSERVED DURING SET OXIDATION OF N,N-DIMETHYL-p-ANISIDINE
Ciminale, F.,Curci, R.,Portacci, M.,Troisi, L.
, p. 2463 - 2466 (2007/10/02)
During SET oxidation of the title compound, N,N,N'-trimethyl-N'-(4-methoxyphenyl)-1,4-phenylendiamine radical cation was detected by e.s.r.; this derives from an oxidatively activated nucleophilic substitution on N,N-dimethyl-p-anisidine.Revised e.s.r. parameters for N,N-dimethyl-p-anisidinium radical are also reported.
