5454-78-4

Usage

Uses

Used in Organic Synthesis:
2-methylcyclopentane-1-carboxylic acid is used as a key intermediate in organic synthesis for the production of various chemical compounds. Its unique structure allows for versatile chemical reactions, making it a valuable component in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 2-methylcyclopentane-1-carboxylic acid is utilized as a starting material or building block for the development of new drugs. Its potential biological activity and unique structural features make it a promising candidate for the discovery of novel therapeutic agents.
Used in Material Science:
2-methylcyclopentane-1-carboxylic acid may also have applications in the development of new materials, such as polymers, coatings, and adhesives. Its chemical properties and reactivity can contribute to the creation of innovative materials with improved performance characteristics.
Used in Flavor and Fragrance Industry:
In the production of flavors and fragrances, 2-methylcyclopentane-1-carboxylic acid can be used as a key component to create unique and complex scents. Its chemical structure allows for the development of new aroma compounds, enhancing the sensory experience in various consumer products.

InChI:InChI=1/C7H12O2/c1-5-3-2-4-6(5)7(8)9/h5-6H,2-4H2,1H3,(H,8,9)

Upstream product

• 201230-82-2 carbon monoxide 
• 110-83-8 cyclohexene 
• 71-43-2 benzene 
• 67886-24-2 (+/-)-cyclopent-2-enecarboxylic acid 
• 74-88-4 methyl iodide 

Downstream Products

• 344243-49-8 2-methylcyclopentanecarbonyl chloride 
• 1601-00-9 methyl 2-methylcyclopentyl ketone 

Relevant academic research and scientific papers

(Lig)Ni(0) induced preparation of mono- and dicarboxylic acids from cyclopentene and carbon dioxide

Cyclopentene is shown to be an ideal substrate for coupling reactions with (Lig)nickel(0) systems. By variation of the ligands and addition of promoters, it is possible by successive application of carbon dioxide or carbon monoxide to prepare highly selectively series of cyclopentane- and cyclopentenecarboxylic acids (six examples), 4, 5, 6, 11, 14, 15, cyclopentanedicarboxylic acids (three examples), 7, 8, 12, or 2-hydroxycyclopentanecarboxylic acid (9) in good yields. The C5-skeleton is retained in the products.

Stereo- and enantioselectivity in catalytic hydrogenolysis of chiral substituted ferrocenes to give cyclopentanes

The catalytic hydrogenolysis of 1,2-disubstituted ferrocenes having planar chirality and functional groups such as carboxyl (including ester) or tertiary amino proceeds under mild conditions (1 atm of H2, Pd/C, CF3COOH, 50 deg C) with the retention of fun

Formylation and Acylation Reactions Catalysed by Trifluoromethanesulphonic Acid

Regioselective formylation of toluene, m- and p-xylene, and mesitylene has been achieved by carbonylation in trifluoromethanesulphonic acid at CO pressures of 90-125 atm.In the case of cumene, the formylation reaction is in competition with disproportionation to form di- and tri-isopropylbenzenes, leading to a complex product mixture.Slow addition of cyclohexene or cyclopentene to a mixture of benzene and CF3SO3H under a high CO pressure affords 4-cyclohexylbenzaldehyde and 4-cyclopentylbenzaldehyde in 34percent and 33percent yieds, respectively, while 2-methylbut-1-ene gives 2,2,3-trimethylindanone (39percent) under similar conditions.When cyclohexene is mixed with the acid under carbon monoxide (120 atm) before addition of benzene the major products are cyclohexyl phenyl ketone and cyclohexenyl cyclohexyl ketones.