54542-51-7

Usage

Uses

Used in Dietary Supplements:
QUERCETIN-3-O-BETA-D-GLUCOPYRANOSYL-6''-ACETATE is used as a dietary supplement for its potential health-promoting effects, including its antioxidant and anti-inflammatory properties.
Used in Cancer Prevention and Treatment:
QUERCETIN-3-O-BETA-D-GLUCOPYRANOSYL-6''-ACETATE is used as a potential cancer-preventive and therapeutic agent, as it has been studied for its role in inhibiting cancer cell growth and promoting apoptosis.
Used in Cardiovascular Disease Management:
QUERCETIN-3-O-BETA-D-GLUCOPYRANOSYL-6''-ACETATE is used as a component in managing cardiovascular diseases due to its potential to improve vascular function and reduce inflammation.
Used in Neurodegenerative Disease Management:
QUERCETIN-3-O-BETA-D-GLUCOPYRANOSYL-6''-ACETATE is used as a potential therapeutic agent in the management of neurodegenerative diseases, as it has been studied for its neuroprotective effects and ability to reduce oxidative stress and inflammation in the brain.
Used in Food and Beverage Industry:
QUERCETIN-3-O-BETA-D-GLUCOPYRANOSYL-6''-ACETATE is used as a natural antioxidant and flavor enhancer in the food and beverage industry, due to its presence in various fruits, vegetables, and herbs.
Used in Pharmaceutical Industry:
QUERCETIN-3-O-BETA-D-GLUCOPYRANOSYL-6''-ACETATE is used as a potential active pharmaceutical ingredient for the development of drugs targeting various diseases, including cancer, cardiovascular, and neurodegenerative diseases, due to its diverse biological activities.

Upstream product

• 482-35-9 isoquercetin 
• 64-19-7 acetic acid 
• 108-05-4 vinyl acetate 
• 96862-01-0 quercetin 3-O-(6′′-O-malonyl)-β-glucopyranoside 

Downstream Products

• 18705-98-1 3',4',5,7-tetra-O-acetylquercetin 3-O-(2'',3'',4'',6''-tetra-O-acetyl-β-D-glucopyranoside) 

Relevant academic research and scientific papers

Isoquercitrin esters with mono- or dicarboxylic acids: Enzymatic preparation and properties

A series of isoquercitrin (quercetin-3-O-β-D-glucopyranoside) esters with mono- or dicarboxylic acids was designed to modulate hydro- and lipophilicity and biological properties. Esterification of isoquercitrin was accomplished by direct chemoenzymatic re

Enzymatic acylation of flavonoids: Effect of the nature of the substrate, origin of lipase, and operating conditions on conversion yield and regioselectivity

The conversion yield at equilibrium, the initial rate, and the regioselectivity of the enzymatic acetylation of aglycone flavonoids (quercetin, naringenin, hesperetin, and chrysin) were investigated and compared to those obtained with a glycosylated one (isoquercitrin). The effects of a wide range of operating conditions were quantified. Fourier transform infrared spectrometry (FT-IR), NMR, and high performance liquid chromatography electrospray ionization mass spectrometry (HPLC-ESI-MS) analyses showed that for glycosylated flavonoids, in the presence of Candida antarctica (CAL-B), the acetylation occurred on the 2″-OH, 3″-OH, and 6″-OH of the glucose part, while with Pseudomonas cepacea lipase (PSL-C) acetylation takes place on 6″-OH of the sugar and 4′-OH of the B-ring. For aglycone flavonoids, the acetylation occurred only with PSL-C on 4′-OH, 3′-OH, and 7-OH hydroxyls. The conversion yield and the number and the relative proportions of the synthesized products were found dependent on the nature of the enzyme, the molar ratio, and the flavonoid structure. The initial rate was affected only by the origin of the enzyme.

DECARBOXYLATION AND EXCHANGE REACTIONS IN FLAVONOID GLYCOSIDE MALONATES

Flavonoid malonylglycosides lose carbon dioxide and give the corresponding flavonoid acetylglycosides under conditions that are often used in determining their NMR spectra (DMSO-d6 at 80-100 deg C).If the solvent contains exchangeable deuterium the malonyl methylene protons may exchange and trideuterioacetyl derivatives form.The NMR spectra of these substances should be run initially at ambient temperature in the absence of solvents containing exchangeable deuterium.Key Word Index - Gerbera jamesonii; Compositae; Ipomoea tricolor; Convolvulaceae; NMR; decarboxylation; proton-deuterium exchange; flavonoid malonylglycosides.