545424-39-3Relevant academic research and scientific papers
CYCLOALKANE-1,3-DIAMINE DERIVATIVE
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Paragraph 1413-1415; 1420, (2021/09/03)
The present invention provides a compound or a pharmaceutically acceptable salt thereof having an inhibitory action on the interaction between menin and an MLL protein. The compound represented by the formula (1) or a pharmaceutically acceptable salt thereof. wherein, in the formula (1), the dotted circle, R1, R2, R3, R4, R5, R6, R7, R8, Ring Q1, W, m and n are each as defined in the description.
Palladium-catalyzed direct (hetero)arylation of ethyl oxazole-4- carboxylate: An efficient access to (hetero)aryloxazoles
Verrier, Cecile,Martin, Thibaut,Hoarau, Christophe,Marsais, Francis
supporting information; experimental part, p. 7383 - 7386 (2009/05/07)
(Chemical Equation Presented) A straightforward route toward 2-(hetero)arylated and 2,5-di(hetero)arylated oxazoles through regiocontrolled palladium-catalyzed direct (hetero)arylation of ethyl oxazole-4-carboxylate with iodo-, bromo-, and chloro(hetero)a
Diaminopyrimidine derivatives as growth hormone secrectgogue receptor (GHS-R) antagonists
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Page/Page column 48, (2010/02/13)
The present invention is related to compounds of formula (I), or a therapeutically suitable salt or prodrug thereof, the preparation of the compounds, compositions containing the compounds and the use of the compounds in the prevention or treatment of disorders regulated by the action of ghrelin receptor, including Prader-Willi syndrome, eating disorder, weight gain, weight-loss maintainance following diet and exercise, obesity, and disorders associated with obesity such as noninsulin dependent diabetes mellitus.
6-O-acyl ketolide antibacterials
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, (2008/06/13)
6-O-Acyl ketolide antibacterials of the formula: wherein R1, R2, R3, R4, W, X, X′, Y, and Y′ are as described herein and in which the substituents have the meaning indicated in the description. These compounds are useful as antibacterial agents.
