54561-73-8

Basic information

• Product Name: Benzenepropanoic acid, a-cyano-b-phenyl-, methyl ester
• CAS NO: 54561-73-8
• Molecular Formula: C17H15NO2
• Molecular Weight: 265.312
• Mol File: 54561-73-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzenepropanoic acid, a-cyano-b-phenyl-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenepropanoic acid, a-cyano-b-phenyl-, methyl ester(54561-73-8)
• EPA Substance Registry System: Benzenepropanoic acid, a-cyano-b-phenyl-, methyl ester(54561-73-8)

Safety Data

• Hazardous Substances Data: 54561-73-8(Hazardous Substances Data)

Upstream product

• 14442-37-6 methyl α-cyano-β,β-diphenyl acrylate 
• 925-90-6 ethylmagnesium bromide 
• 1462-75-5 3-phenylpropylmagnesium bromide 
• 15890-72-9 laurylmagnesium bromide 
• 926-62-5 isobutylmagnesium bromide 
• 109-72-8 n-butyllithium 
• 693-03-8 n-butyl magnesium bromide 

Relevant articles and documents

A hydride transfer reaction from salts of carbanions to activated olefins

A novel reaction - a β-elimination of a hydride ion from carbanion salts RM (R = Li, MgBr) and R2N-Li+, and its transfer to tetra-substituted activated olefins of the type Ar2C=C(CN)CO2R (R = Me,Et), was studied. Yields of the reduced H--acceptor were used to follow the extent of the H--transfer reaction. A competing Michael addition reaction of RM to the activated olefin also took place. The effects of the solvation properties of the solvent, the reaction temperature, the positive counter-ion, and of various structural features of the H--donor and the H--acceptor, were studied. The structural factors associated with both reactants, played a critically significant role due to the bimolecularity of the reaction. A benzyl substituent at C(β) of RM, a methine-type β-carbon, or a small size of R of RM, resulted in a relatively high extent of the H--transfer reaction. It is suggested that the presently studied β-elimination of a hydride ion takes place by a bimolecular E2cB-type mechanism.