5458-84-4

Basic information

• Product Name: 2-IODO-5-NITROANISOLE
• Synonyms: 2-IODO-5-NITROANISOLE;2-IODO-5-NITROANISOLE 97%;4-Iodo-3-methoxynitrobenzene;1-Iodo-2-methoxy-4-nitrobenzene;I-Iodo-2-Methoxy-4-nitrobenzene;4-Iodo-3-Methoxynitrobenzene[2-Iodo-5-nitroanisole];2-Iodo-5-nitroanisole【4-Iodo-3-methoxynitrobenzene】
• CAS NO: 5458-84-4
• Molecular Formula: C₇H₆INO₃
• Molecular Weight: 279.03
• Product Categories: Anisole;Anisoles, Alkyloxy Compounds & Phenylacetates;Iodine Compounds;Nitro Compounds
• Mol File: 5458-84-4.mol

Chemical Properties

• Melting Point: 128-130°C
• Boiling Point: 341.2 °C at 760 mmHg
• Flash Point: 160.1 °C
• Appearance: /
• Density: 1.893 g/cm³
• Vapor Pressure: 0.000162mmHg at 25°C
• Refractive Index: 1.629
• Storage Temp.: Refrigerated.
• CAS DataBase Reference: 2-IODO-5-NITROANISOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-IODO-5-NITROANISOLE(5458-84-4)
• EPA Substance Registry System: 2-IODO-5-NITROANISOLE(5458-84-4)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 5458-84-4(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-IODO-5-NITROANISOLE is used as a synthetic intermediate for the development of various pharmaceuticals. Its unique structure allows for the creation of new drug molecules with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 2-IODO-5-NITROANISOLE is used as a precursor in the synthesis of agrochemicals, contributing to the development of effective pesticides and other agricultural products.
Used in Dye Industry:
2-IODO-5-NITROANISOLE is utilized as a building block in the production of dyes, enabling the creation of a variety of colorants for different applications, including textiles, plastics, and printing inks.
Used in Research and Chemical Analysis:
2-IODO-5-NITROANISOLE is employed as a research compound in various scientific studies, aiding in the understanding of chemical reactions and the development of new methodologies in chemical analysis.
Safety Precautions:
Due to the potential health and environmental hazards associated with 2-IODO-5-NITROANISOLE, it is crucial to handle 2-IODO-5-NITROANISOLE with caution. Proper safety measures, including the use of personal protective equipment, should be implemented to minimize risks during its synthesis, storage, and application.

InChI:InChI=1/C7H6INO3/c1-12-7-4-5(9(10)11)2-3-6(7)8/h2-4H,1H3

Upstream product

• 197243-46-2 2-iodo-5-nitrophenol 
• 121-88-0 5-Nitro-2-aminophenol 
• 869373-72-8 C₁₄H₁₄N₄O₄ 
• 869373-61-5 1-(4-methylphenyl)-3-(2-methoxy-4-nitrophenyl)-2-triazene 

Downstream Products

• 51230-16-1 2-methoxy-4-nitro-1-phenoxy-benzene 
• 892870-61-0 1-[3-(2-methoxy-4-nitro-phenyl)-prop-2-ynyl]-pyrrolidine 
• 1172639-65-4 5-(2-methoxy-4-nitro-phenyl)-2-methyl-thiazole 
• 453560-74-2 2-methoxy-4-nitro-1-(trifluoromethyl)benzene 
• 190198-15-3 1-(2-methoxy-4-nitrophenyl)-1H-imidazole 
• 1240613-93-7 4-(2,4-dichlorophenoxy)-3-methoxynitrobenzene 
• 4163-77-3 (2-methoxy-4-nitrophenyl)(methyl)sulfane 
• 1124148-89-5 C₈H₆F₃NO₃S 
• 857620-64-5 acetic acid-(5-methoxy-2-nitro-4-phenoxy-anilide) 
• 857590-98-8 5-methoxy-2-nitro-4-phenoxy-aniline 
• 857620-62-3 acetic acid-(3-methoxy-4-phenoxy-anilide) 
• 733729-21-0 3-methoxy-4-phenoxy-phenylamine 

Relevant articles and documents

2-Methoxy-4-nitrobenzenediazonium salt as a practical diazonium-transfer agent for primary arylamines via tautomerism of 1,3-diaryltriazenes: Deaminative iodination and arylation of arylamines without direct diazotization

1,3-Diaryltriazenes, prepared from a 2-methoxy-4-nitrobenzenediazonium salt and primary arylamines, exist as "azo-transfer" tautomers in which the 2-methoxy-4-nitrophenyl group is present on the saturated nitrogen atom and forms a hydrogen bond between the 2-methoxy group and the N-H moiety. The synthetic utility of the diazonium salt as a practical diazonium-transfer agent for primary arylamines via tautomerism of the 1,3-diaryltriazenes has been demonstrated by the deaminative iodination and arylation of the arylamines without direct diazotization. The starting 2-methoxy-4-nitrophenylamine can be easily recovered after the reactions.