54582-33-1

Basic information

• Product Name: 1H-Pyrrole,1,1-carbonylbis-(9CI)
• Synonyms: 1H-Pyrrole,1,1-carbonylbis-(9CI)
• CAS NO: 54582-33-1
• Molecular Formula: C₉H₈N₂O
• Molecular Weight: 160.17262
• Product Categories: AMIDE
• Mol File: 54582-33-1.mol
• Article Data: 10

Chemical Properties

• Melting Point: 160-161 °C (sublm)
• Boiling Point: 78-81 °C(Press: 1 Torr)
• Appearance: /
• Density: 1.15±0.1 g/cm3(Predicted)
• PKA: -7.10±0.70(Predicted)
• CAS DataBase Reference: 1H-Pyrrole,1,1-carbonylbis-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrole,1,1-carbonylbis-(9CI)(54582-33-1)
• EPA Substance Registry System: 1H-Pyrrole,1,1-carbonylbis-(9CI)(54582-33-1)

Safety Data

• Hazardous Substances Data: 54582-33-1(Hazardous Substances Data)

Upstream product

• 32315-10-9 bis(trichloromethyl) carbonate 
• 16199-06-7 potassium pyrrolide 
• 109-97-7 pyrrole 
• 530-62-1 1,1'-carbonyldiimidazole 
• 102-09-0 bis(phenyl) carbonate 
• 75-44-5 phosgene 

Downstream Products

• 5145-65-3 N-benzoylpyrrole 
• 86734-19-2 N-(1-hydroxy-1-benzyl)pyrrole 
• 83819-26-5 Diphenyl-pyrrol-1-yl-methanol 
• 114374-36-6 N-acryloylpyrrole 
• 497147-42-9 trans-N-crotonylpyrrole 
• 627546-31-0 1-(1H-pyrrol-1-yl)-2-(triphenylphosphoranylidene)ethanone 
• 1338700-86-9 (Z)-methyl 3-(4-methoxyphenyl)-2-(1H-pyrrole-1-carbonyl)acrylate 
• 931-40-8 4-hydroxymethyl-1,3-dioxolan-2-one 
• 448211-19-6 1-ethyl-1H-imidazo[4,5-b]pyridin-2(3H)-one 
• 603-23-6 3-phenyl-2,4-(1H,3H)-quinazolinedione 
• 70971-72-1 (4-methoxyphenyl)-(1H-pyrrol-1-yl)methanone 
• 70971-70-9 (1H-pyrrol-1-yl)(p-tolyl)methanone 

Relevant articles and documents

Aluminum(III)-Catalyzed, Formal Homo-Nazarov-Type Ring-Opening Cyclizations toward the Synthesis of Functionalized Tetrahydroindolizines

A general approach to functionalized 5,6,7,8-tetrahydroindolizines (THIs) is disclosed. The THIs are directly formed from Al(OTf)3-catalyzed, formal homo-Nazarov-type ring-opening cyclizations of N-pyrrolyl cyclopropyl malonamides. The THI products were stable to silica gel chromatography and isolated in up to 97% yield with diastereomeric ratios up to 4.0:1. The cyclization demonstrates good substrate scope as aryl, heteroaryl, gem-dialkyl, heteroatomic, and silylmethyl donor groups on the cyclopropane are tolerated. Moreover, the protocol is both pharmaceutically relevant and environmentally friendly as a cheap, earth-abundant metal catalyst is used along with acetonitrile as a greener solvent.

Tetrakis-(N-pyrrolyl)methane: Structurally Important Member of the C(NR2)4 Family

The structural motif C(NR2)4 is rare in chemistry. The formation, NMR spectroscopic characteristics, and X-ray structure are reported for a structurally interesting member of this family, namely tetrakis-(N-pyrrolyl)methane.

Carbonic acid diester activation by polymer-bound DBU and its relevance to catalytic N-carbonylation of N-heteroaromatics: Direct evidence for an elusive N-carboxy-substituted amidinium cation intermediate

Polymer-bound DBU (PS-DBU, DBU = 1,8-diazabicyclo[5.4.0]undec-7-ene) is an effective and selective catalyst for solventless N-phenoxycarbonylation of N-heteroaromatics (pyrrole (1), indole (2), and carbazole (3)) with diphenyl carbonate (DPC), used as an