54583-69-6

Basic information

• Product Name: dimethyl-2,5 formyl-3 furanne
• Synonyms: dimethyl-2,5 formyl-3 furanne
• CAS NO: 54583-69-6
• Molecular Weight: 124.139
• Mol File: 54583-69-6.mol

Chemical Properties

• CAS DataBase Reference: dimethyl-2,5 formyl-3 furanne(CAS DataBase Reference)
• NIST Chemistry Reference: dimethyl-2,5 formyl-3 furanne(54583-69-6)
• EPA Substance Registry System: dimethyl-2,5 formyl-3 furanne(54583-69-6)

Safety Data

• Hazardous Substances Data: 54583-69-6(Hazardous Substances Data)

Upstream product

• 5436-21-5 acetylacetaldehyde dimethyl acetal 
• 123-38-6 propionaldehyde 
• 78-94-4 methyl vinyl ketone 
• 50990-93-7 2,5-dimethyl-furan-3-carbonyl chloride 
• 28562-70-1 2,5-dimethyl-furan-3-carboxanilide 
• 1003-96-9 2,5-dimethyl-3-(hydroxymethyl)furan 
• 498-60-2 furan-3-carboxaldehyde 
• 5612-67-9 2-methyl-furan-3-carboxaldehyde 
• 74-88-4 methyl iodide 
• 110-13-4 2,5-hexanedione 
• 68-12-2 N,N-dimethyl-formamide 
• 79190-42-4 2,5-Dimethyl-N-phenyl-furan-3-carboximidoyl chloride 

Downstream Products

• 1150224-53-5 cyclohexyl(2,5-dimethylfuran-3-yl)methanol 

Relevant articles and documents

A new method for the synthesis of furan derivatives

Substituted 2-chloro-4-formyl-5-arylfuran and 2,5-dimethyl-3-formylfuran derivatives were synthesised from their corresponding substituted 3-benzoylpropionic acid and acetonylacetone using Vilsmeier reagent in good yields.

HETEROCYCLIC COMPOUND

The present invention provides a heterocyclic compound represented by the following formula (I), which has a glucagon antagonistic action and is useful for the prophylaxis or treatment of diabetes and the like, a compound represented by wherein ring A is an optionally substituted benzene ring and the like; Y is a nitrogen atom and the like; X is -O- and the like; R4 is a hydrogen atom and the like; R5 and R6 are each independently a hydrogen atom and the like; R1 is an optionally substituted hydrocarbon group and the like; R2 is a hydrogen atom and the like; and R3 is -(CH2)3-COOH and the like, or a salt thereof.

Synthesis of substituted furoates from acrylates and aldehydes by Pd(OAc)2/HPMoV/CeCl3/O2 system

(Chemical Equation Presented) A new synthetic method of substituted furoates from acrylates and aldehydes was developed by Pd-(OAc)2 combined with molybdovanadophosphoric acid and Lewis acid under atmospheric dioxygen. The reaction was found to proceed through the palladium-catalyzed acetalization of acrylates with methanol followed by the reaction of the resulting acetals with aldehydes.

Lithiation of Heterocycles Directed by α-Amino Alkoxides

The addition of heterocyclic aromatic aldehydes to certain lithium dialkylamides gave α-amino alkoxides that were ring-lithiated with butyllithium.Alkylation and hydrolysis provided ring-substituted heterocyclic aromatic aldehydes via a one-pot reaction.The metalation of α-amino alkoxides derived from thiophenecarboxaldehydes, furaldehydes, N-methylpyrrolecarboxaldehydes, and indolecarboxaldehydes was examined.The regioselectivity of the lithiation, was dependent on the heterocycle, the amine component of the α-amino alkoxide, and the metalation conditions.A novel N-methyl metalation of α-amino alkoxides derived from N-methylpyrrole-2-carboxaldehyde and N-methylindole-2-carboxaldehyde was achieved when N,N,N'-trimethylethylenediamine was used as the amine component for in situ formation of the α-amino alkoxides.The novel directed N-methyl lithiations are attributed to an intramolecular TMEDA-like assisted metalation.

Transformation thermique des β-(methyl-2 furyl)-3 acryloylazides: Nouveau mode de formation de certaines pyrimidines

In boiling diphenyl ether, β-3-(2-methylfuryl)acryloylazides were not transformed to the expected furopyridones according to the Eloy and Deryckere reaction but 5-substituted pyrimidine-2,4-diones, generated by dimerization of vinyl isocyanates issued from Curtius reaarangement of the starting material, were obtained.