54584-22-4

Basic information

• Product Name: 6-HYDROXY-2-METHYLINDOLE
• Synonyms: 6-HYDROXY-2-METHYLINDOLE ;2-Methyl-1H-indol-6-ol;6-Hydroxy-2-Methyl-1H-indole;1H-Indol-6-ol, 2-methyl-
• CAS NO: 54584-22-4
• Molecular Formula: C₉H₉NO
• Molecular Weight: 147.17386
• Mol File: 54584-22-4.mol

Chemical Properties

• Boiling Point: 344.843 °C at 760 mmHg
• Flash Point: 162.355 °C
• Appearance: /
• Density: 1.262 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.704
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 10.23±0.40(Predicted)
• CAS DataBase Reference: 6-HYDROXY-2-METHYLINDOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-HYDROXY-2-METHYLINDOLE(54584-22-4)
• EPA Substance Registry System: 6-HYDROXY-2-METHYLINDOLE(54584-22-4)

Safety Data

• Hazardous Substances Data: 54584-22-4(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Applications:
6-Hydroxy-2-methylindole is used as an active pharmaceutical ingredient for its antibacterial and anti-inflammatory properties, making it a potential candidate for the development of new drugs to treat various infections and inflammatory conditions.
Used in Traditional Chinese Medicine:
6-Hydroxy-2-methylindole is used as a pigment in traditional Chinese medicine, where its yellow color is utilized for various medicinal purposes.
Used in Cancer Research:
6-Hydroxy-2-methylindole is used as a research compound in the study of its potential role in inhibiting cancer cell growth, with the aim of developing new anti-cancer therapies.
Used in Pigment Industry:
6-Hydroxy-2-methylindole is used as a natural yellow pigment in various industries, such as cosmetics, textiles, and paints, due to its vibrant color and unique properties.
Used in Drug Delivery Systems:
In the future, 6-Hydroxy-2-methylindole may be used in drug delivery systems to improve the bioavailability and therapeutic outcomes of its anti-cancer properties, by employing various organic and metallic nanoparticles as carriers for targeted delivery to cancer cells.

InChI:InChI=1/C9H9NO/c1-6-4-7-2-3-8(11)5-9(7)10-6/h2-5,10-11H,1H3

Upstream product

• 1968-13-4 2-methyl-6-methoxy-1H-indole 
• 144-55-8 sodium hydrogencarbonate 

Downstream Products

• 57330-46-8 6-(phenylmethoxy)-2-methylindole 

Relevant articles and documents

FUSED HETEROCYCLIC DERIVATIVE AND USE THEREOF

The present invention provides a fused heterocyclic derivative having a potent kinase inhibitory activity and use thereof. A compound represented by the formula (I): wherein each symbol is as defined in the specification, except a particular compound, or a salt thereof, and a pharmaceutical agent containing the compound or a prodrug thereof, which is a kinase (VEGFR, VEGFR2, PDGFR, Raf) inhibitor, an angiogenesis inhibitor, an agent for the prophylaxis or treatment of cancer, a cancer growth inhibitor or a cancer metastasis suppressor.

Process for dyeing keratin fibres with a monohydroxyindole associated with an iodide and hydrogen peroxide

Process for dyeing keratin fibres consisting in applying on these fibres a composition (A) containing at least one indole colorant of formula: STR1 where R1 =H or C1 -C4 alkyl; R2 and R3, which may be identical or different, denote H, C1 -C4 alkyl, carboxyl or alkoxycarbonyl; or a salt or a precursor of a compound (I), associated, either with iodide ions, or with H2 O2 ; application of composition (A) being preceded or followed by the application of a compound (B) which contains, either H2 O2 at a pH of 2 to 12 when (A) contains iodide ions, or iodide ions at a pH of 2 to 11 when (A) contains H2 O2. This process allows particularly powerful and resistant dyes to be made.

In pursuit of non narcotic analgetic and antiinflammatory agents. 1 carboxyalkyl 3 acylindoles

The synthesis and study of different carboxyalcoyl 1 acyl 3 indoles has led to molecules endowed with analgesic properties associated with an anti inflammatory action of variable importance. In particular carboxymethyl 1 p chlorobenzoyl 3 methoxy 6 indole (RU 3959) has a strong analgesic activity and a remarkable tolerance which have been confirmed in clinical trials.