545882-50-6

Upstream product

• 107-21-1 ethylene glycol 
• 172324-67-3 3-benzyloxymethyl-cyclobutanone 
• 14593-43-2 benzyl allyl ether 
• 23761-23-1 3-oxocyclobutanecarboxylic acid 
• 198995-91-4 benzyl 3-oxocyclobutane-1-carboxylate 
• 172324-66-2 3-(benzyloxymethyl)-2,2-dichlorocyclobutanone 

Downstream Products

• 175021-11-1 (3,3-bis-methoxy-cyclobutyl)methanol 
• 545882-60-8 (5,8-dioxaspiro[3.4]octan-2-yl)methanol 
• 172324-67-3 3-benzyloxymethyl-cyclobutanone 

Relevant academic research and scientific papers

SUBSTITUTED SPIROPYRIDO[1,2-a]PYRAZINE DERIVATIVE AND PHARMACEUTICAL USE OF SAME AS HIV INTEGRASE INHIBITOR

Provided is a substituted spiropyrido[1,2-a]pyrazine derivative or a pharmaceutically acceptable salt thereof, which is useful as an anti-HIV agent. The present invention relates to a compound represented by the following formula [I] or [II] or a pharmace

PYRAZOLO (3, 4-B) PYRIDINE DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS

The present invention relates to phosphodiesterase (PDE) type 4, phosphodiesterase (PDE) type 7 and dual PDE type 4 /PDE type 7 inhibitors. Compounds disclosed herein having the structure of Formura 1: can be useful in the treatment, prevention, inhibitio

An efficient route to 3-substituted cyclobutanone derivatives

An efficient route to 3-(hydroxymethyl)cyclobutanone acetals via a [2+2] cycloaddition reaction is reported. The dramatic effect of different diol acetals on benzyl deprotection is discussed. Efficient synthesis of two synthetically useful intermediates, 3-methylenecyclobutanone acetal and 3-(bromomethyl)cyclobutanone, are provided.