5460-45-7

Basic information

• Product Name: 2-ethylhexyl formate
• Synonyms: 2-ethylhexyl formate;Formic acid 2-ethylhexyl ester;Nsc21825
• CAS NO: 5460-45-7
• Molecular Formula: C₉H₁₈O₂
• Molecular Weight: 158.23802
• EINECS: 226-740-6
• Mol File: 5460-45-7.mol
• Article Data: 9

Chemical Properties

• Melting Point: -39.1°C (estimate)
• Boiling Point: 183.34°C (estimate)
• Flash Point: 71.8°C
• Appearance: /
• Density: 0.8809 (estimate)
• Vapor Pressure: 0.409mmHg at 25°C
• Refractive Index: 1.4040 (estimate)
• CAS DataBase Reference: 2-ethylhexyl formate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-ethylhexyl formate(5460-45-7)
• EPA Substance Registry System: 2-ethylhexyl formate(5460-45-7)

Safety Data

• Hazardous Substances Data: 5460-45-7(Hazardous Substances Data)

Usage

General Description

2-Ethylhexyl formate is a chemical compound with the formula C10H20O2. It is an ester formed by the condensation of 2-ethylhexanol and formic acid. This colorless liquid has a fruity odor and is commonly used as a flavoring agent in the food industry. It is also used as a solvent and intermediate in the production of various chemicals. 2-Ethylhexyl formate is flammable and should be handled with care due to its potential hazards. It is important to follow safety guidelines when working with this chemical to minimize the risk of exposure and adverse effects.

InChI:InChI=1/C9H18O2/c1-3-5-6-9(4-2)7-11-8-10/h8-9H,3-7H2,1-2H3

Upstream product

• 123-05-7 d,l-2-ethylhexanal 
• 100528-70-9 2-(2-ethylhexyloxy)-tetrahydro-2H-pyran 
• 109-94-4 formic acid ethyl ester 
• 104-76-7 2-Ethylhexyl alcohol 
• 56136-01-7 tri-2-ethylhexyl orthoformate 
• 25234-36-0 2-decyltetradec-2-enal 
• 68-12-2 N,N-dimethyl-formamide 
• 98-88-4 benzoyl chloride 
• 100011-12-9 N-((2-ethylhexyloxy)methylidene) dimethyliminium chloride 
• 64-18-6 formic acid 

Relevant articles and documents

ETHERIFICATION PROCESS

The present invention relates to a process for preparing ethers, particularly unsymmetrical ethers, and preferably ethers suitable for use as base stocks for lubricant compositions. In particular, the process involves the reaction of an α,β-unsaturated aldehyde with a trihydrocarbyl orthoester to form an α,β-unsaturated acetal and conversion of the α,β- unsaturated acetal to an ether through hydrogenation and hydrogenolysis.

Formamides as Lewis Base Catalysts in SNReactions—Efficient Transformation of Alcohols into Chlorides, Amines, and Ethers

A simple formamide catalyst facilitates the efficient transformation of alcohols into alkyl chlorides with benzoyl chloride as the sole reagent. These nucleophilic substitutions proceed through iminium-activated alcohols as intermediates. The novel method, which can be even performed under solvent-free conditions, is distinguished by an excellent functional group tolerance, scalability (>100 g) and waste-balance (E-factor down to 2). Chiral substrates are converted with excellent levels of stereochemical inversion (99 %→≥95 % ee). In a practical one-pot procedure, the primary formed chlorides can be further transformed into amines, azides, ethers, sulfides, and nitriles. The value of the method was demonstrated in straightforward syntheses of the drugs rac-Clopidogrel and S-Fendiline.

Efficient one-step conversion of tetrahydropyranyl ethers into acetates and formates in the presence of potassium dodecatungstocobaltate K 5CoW12O40·3H2O

Tetrahydropyranyl ethers derived from primary alcohols were directly and efficiently converted into the corresponding acetates and formates by the action of ethyl acetate, acetic acid, acetic anhydride, and ethyl formate in the presence of a catalytic amount of potassium dodecatungstocobaltate K 5CoW12O40 ? 3H2O. Tetrahydropyranyl ethers derived from secondary alcohols and phenols can also be transformed into the corresponding acetates with the use of acetic anhydride, but K5CoW12O40 ? 3H2O was ineffective for esterification with ethyl acetate, acetic acid, and ethyl formate.