54620-48-3Relevant academic research and scientific papers
Synthesis of Aryl Amine Derivatives from Benzyl Nitriles via Electrocyclization of in Situ Generated N-Silyl Ketene Imines
Yoshimura, Fumihiko,Abe, Taiki,Tanino, Keiji
supporting information, p. 1630 - 1633 (2016/04/26)
The previously unexplored reactivity of N-silyl ketene imines in organic synthesis is reported. Benzyl nitriles containing an alkenyl or aryl group at the ortho position were smoothly converted into aryl amines in good yields under two sets of mild silyla
Synthesis of mono-substituted derivatives of 6-aminoquinoline
Lan, Tian,Yuan, Xian Xia,Yu, Jiang Hong,Jia, Chao,Wang, Yu Shi,Zhang, Hui Juan,Ma, Zi Feng,Ye, Wei Dong
scheme or table, p. 253 - 255 (2012/01/04)
Several 6-aminoquinoline derivatives, which could be used in drug design, have been synthesized. The reaction conditions were comparatively studied, and the p-chloroaniline was used as optimum oxidant in Skraup-Doebner-Von Miller reaction. The nitro group was reduced effectively by SnCl2 with no halo-removed occurred.
PHOTOLYSIS OF QUINOLYL AND ISOQUINOLYL AZIDES IN ALCOHOLS CONTAINING SULFURIC ACID
Sawanishi, Hiroyuki,Hirai, Toyoko,Tsuchiya, Takashi
, p. 2071 - 2074 (2007/10/02)
Photolysis of 3-azidoquinoline, 4-azidoisoquinoline, and 4-azidoquinoline N-oxide in alcohols containing sulfuric acid gave the corresponding α-alkoxy amino compounds (2,3,5,7) via nitrenium ion intermediates.In contrast, 3-azidoquinoline N-oxide, 5-azido and 8-azidoquinoline, and 5-azidoquinoline, upon irradiation under similar conditions, gave the different type of α-alkoxy amino compounds such as 9 and 13 via azirine or azacycloheptatetraene intermediates.
