54638-91-4

Upstream product

• 104-55-2 3-phenyl-propenal 
• 95-55-6 2-amino-phenol 
• 694472-13-4 trans-N-(3-Phenyl-2-propenylidene)-o-aminophenol 
• 141-97-9 ethyl acetoacetate 

Downstream Products

• 888-92-6 2-styrylbenzo[d]oxazole 
• 122127-30-4 2-(1-Oxo-5,6-diphenyl-5,6-dihydro-1H-1λ⁴-[1,2,6]thiadiazin-2-yl)-phenol 
• 858365-87-4 C₂₁H₂₈NO₄P 

Relevant academic research and scientific papers

Cinnamylaldehyde derivative fluorescent probe compound as well as preparation method and application thereof

The invention discloses a cinnamylaldehyde derivative fluorescent probe compound, a preparation method and application thereof. The cinnamylaldehyde derivative fluorescent probe compound has a structural formula shown in the specification, the cinnamylald

Hemoglobin: A New Biocatalyst for the Synthesis of 2-substituted Benzoxazoles via Oxidative Cyclization

Efficient and mild synthesis of a series of 2-substituted benzoxazoles via oxidative cyclization catalyzed by hemoglobins reported here for the first time. Satisfactory yields (84 %–97 %) and mild reaction conditions make this method highly viable for practical applications.

New hockey stick shaped amino allylidene (?N?CH?CH?CH) based compounds: Effect of linkage group on mesomorphic properties

Two nonlinear hockey stick shaped homologous series based on three linking groups have been synthesized and characterized by elemental analyses and spectroscopic techniques. The mesomorphic properties of these compounds were observed by polarizing optical microscopy (POM) and differential scanning calorimetry (DSC). In this present investigation, we have synthesized two homologous series viz. 2-((3-phenyl allylidene) amino) phenyl 4-((4-n-alkoxy benzylidene) amino) benzoate (series-1) and 4-((2-((3-phenyl allylidene) amino) phenoxy) carbonyl) phenyl-4-n-alkoxy benzoate (series-2). Both the series are differing with respect to first linking group. In series-1, comp.C4-C18 shows nematic as well as smectic phase while in series-2, comp.C10-C16 shows smectic and nematic phase while comp.C4-C18 shows only nematic phase.

Mixed ligand complexes with 4-aminoantipyrine derivatives to combat natural antioxidant system: Synthesis, characterization and biological studies

Novel 4-aminoantipyrine based mixed ligand metal complexes with the Schiff bases of L1 (L1-4-aminoantipyrine with furfuraldehyde and L2/L3/L4/L5 are and L2-2-aminophenol with salicylaldehyde, L3-2-aminophenol with cinnamaldehyde, L4-2-aminobenzothiazole with salicylaldehyde, L5-2-aminobenzothiazole with cinnamaldehyde) were synthesized. The structures of the mixed ligand complexes were established by analytical and spectral techniques. They were screened for in vitro antimicrobial activity against of bacteria and fungi by disc diffusion method. The interaction of metal complexes with calf thymus-DNA (CT-DNA) was investigated by UV-visible, cyclic voltammetry, viscosity and thermal denaturation studies. DNA interaction studies suggest that metal complex binds to calf thymus-DNA through intercalation mode. Superoxide dismutase activity of these complexes has also been studied. The free ligands and their metal complexes have been tested for in vitro antioxidant activity by the reduction of 1,1-diphenyl-2-picryl hydrazyl (DPPH). The antioxidant activities of the complexes were studied and compared with the activity of ascorbic acid. Copper(II) complex showed superior antioxidant activity than other complexes.

Expedient, catalyst-free, three-component synthesis of fused tetrahydropyridines in water

A catalyst-free, three-component reaction between amino alcohols, 1,3-dicarbonyl compounds and α,β-unsaturated aldehydes was developed for the synthesis of fused tetrahydropyridines in water. The β-enaminone formation-initiated domino sequence afforded ox

An efficient synthesis of 2-substituted benzoxazoles using cerium(III) chloride/sodium iodide as catalyst

An efficient and environmentally benign method for the synthesis of 2-substituted benzoxazoles is reported. The condensation of 2-aminophenol with an aldehyde gave an imine intermediate, which was cyclized and dehydrogenated to 2-substituted benzoxazole with good yield in the presence of CeCl 3 /NaI as catalyst. The one-pot synthesis was carried out in toluene at 100 ° C using O 2 as the oxidant.

Synthesis, spectroscopic and structural studies on N-(2-hydroxyphenyl) cinnamaldimine and some bivalent metal complexes

The bidentate Schiff base, CINOPH, obtained from the condensation of cinnamaldehyde with 2-aminophenol undergoes facile complexation reactions to form MII(CINOP)2 (M= Cu, Ni, Co and Zn). In these complexes coordination is through imi

Hypervalent iodine(III) mediated synthesis of 2-substituted benzoxazoles

2-Substituted benzoxazoles (6a-j, 7a-e, 7j-l) have been synthesized via the oxidative intramolecular cyclization of Schiff's bases (4a-j, 5a-e, 5j-l) using iodobenzene diacetate (IBD) as an oxidant in dry methanol. A one-pot procedure for the synthesis of 6a-j, 7a-e and 7j-l starting from o-aminophenol/p-chloro-o- aminophenol and aldehydes has also been developed.

Photochemical and Thermal Reactions of Aromatic Schiff Bases

The photochemical and thermal reactions of aromatic Schiff bases (SB) prepared from o-aminophenol and aldehydes and from o-aminophenol and ketones are compared.All SB's are converted by light into the corresponding benzoxazolines.For the SB's derived from aldehydes, benzoxazoline formation is a prerequisite to convert them by a second photon into benzoxazoles.In some cases oxygen is not required for this second reaction step.SB's derived from ketones are converted into benzoxazoles by the absorption of just one photon, but only in the presence of oxygen and only if the aliphatic residue R1 of the N=C(R1R2) bridge contains at least two carbon atoms.A radical mechanism is proposed for this reaction.Benzoxazine formation is observed in some cases as a thermal side reaction.The photochemical reactions of the latter were also investigated.