54644-13-2Relevant academic research and scientific papers
A convenient method for synthesis of 5-chloro-2-aryloxazole-4-carbaldehyde with vilsmeier reagent
Jin, Can,Chen, Jun,Su, Weike
, p. 153 - 161 (2011/04/21)
A convenient method for synthesis of 5-chloro-2-aryloxazole-4-carbaldehyde 3 in moderate to good yields had been developed via the Vilsmeier reaction of readily available N-arylglycine 2 at 100 °C, provided a novel route for the construction of nitrogen heterocycles. A series of these compounds were synthesized by this method and optimization of conditions was performed. The Japan Institute of Heterocyclic Chemistry.
Synthesis and Thermolysis of 5-Azido-4-formyloxazoles
L'abbe, Gerrit,Ilisiu, Anna-Maria,Dehaen, Wim,Toppet, Suzanne
, p. 2259 - 2262 (2007/10/02)
5-Azidooxazole-4-carbaldehydes 5a-c have been prepared from the corresponding chloro aldehydes and found to be unstable in solution at room temperature.Whereas the phenyl derivative 5a decomposed with loss of nitrogen and formation of the imine 6 which wa
