5465-08-7

Usage

Uses

Used in Pharmaceutical Industry:
2-(1,3-dioxolan-2-yl)ethanol is used as a solvent and intermediate for the synthesis of various pharmaceutical compounds. Its unique dioxolane ring structure allows for specific interactions with other molecules, facilitating the development of new drugs and improving the efficacy of existing ones.
Used in Agrochemical Industry:
In the agrochemical sector, 2-(1,3-dioxolan-2-yl)ethanol serves as a key intermediate in the production of various agrochemicals. Its ability to form stable complexes with other molecules makes it an essential component in the synthesis of effective and environmentally friendly pesticides and fertilizers.
Used in Polymer Manufacturing:
2-(1,3-dioxolan-2-yl)ethanol is used as a crosslinking agent in the manufacturing of polymers. Its presence in the polymer matrix enhances the mechanical properties and chemical resistance of the final product, making it suitable for a wide range of applications, including automotive, aerospace, and electronics industries.
Used as a Stabilizer in Vinyl Polymer Production:
In the production of vinyl polymers, 2-(1,3-dioxolan-2-yl)ethanol acts as a stabilizer, preventing the degradation of the polymer during processing and improving its overall performance. This contributes to the production of high-quality vinyl polymers with enhanced durability and stability.
It is crucial to handle and store 2-(1,3-dioxolan-2-yl)ethanol with care, as it can pose hazards if not used properly. Proper safety measures and precautions should be taken to ensure the safe use of this versatile compound in various industrial applications.

Upstream product

• 3984-22-3 2-vinyl-1,3-dioxolane 
• 71516-49-9 2-(2-benzyloxyethyl)-1,3-dioxolane 
• 18742-02-4 2-bromo-2-(2-ethyl)dioxolane 
• 4362-36-1 2-(2-chloroethyl)-1,3-dioxolane 

Downstream Products

• 90711-96-9 2-(1,3-dioxolan-2-yl)acetaldehyde 
• 71516-49-9 2-(2-benzyloxyethyl)-1,3-dioxolane 
• 1276099-30-9 5-[2-(1,3-dioxolane-2-yl)-ethyloxy]-methyl-2,2,7,8-tetramethyl-chroman-6-ol 
• 1276099-36-5 6-O-allyl-5-[2-(1,3-dioxolane-2-yl)-ethyloxy]-ethyl-2,2,7,8-chroman-6-ol 
• 108380-64-9 ((E)-3-Bicyclo[2.2.1]hepta-2,5-dien-7-yl-1-[1,3]dioxolan-2-ylmethyl-allyloxy)-tert-butyl-dimethyl-silane 
• 108380-61-6 7-<3'-(dimethyl-t-butylsilyloxy)-4'-(1'',3''-dioxolan-2''-yl)but-1'-ynyl>norbornadiene 
• 108380-62-7 4-Bicyclo[2.2.1]hepta-2,5-dien-7-yl-1-[1,3]dioxolan-2-yl-but-3-yn-2-ol 
• 108380-63-8 (E)-4-Bicyclo[2.2.1]hepta-2,5-dien-7-yl-1-[1,3]dioxolan-2-yl-but-3-en-2-ol 
• 108380-60-5 3-(dimethyl-t-butylsilyloxy)-4-(1,3-dioxolan-2-yl)but-1-yne 
• 108380-59-2 1-(1,3-dioxolan-2-yl)but-3-yn-2-ol 

Relevant academic research and scientific papers

Carbon-13 NMR Spectra of 1,3-Dioxolanes. I-New Parameters for cis- and trans-4-Methyl Groups in 2,4-Disubstituted Derivatives

The 13C NMR spectra of 24 1,3-dioxolane derivatives are reported in an attempt to propose parameters for the C-2, C-4 and C-5 shifts from the 2-Me and 4-Me substituents, based on the ring stereochemistry.These parameters are obtained from simultaneuos equations, and clearly agree with those calculated by the use of pattern molecules.The calculated parameter for the C-4 shift due to a 2-Me group differs notably from that proposed by other workers.KEY WORDS 1,3-dioxolane derivatives 13C NMR Shift parameters

Aminopolycarboxylic acids and derivatives thereof

There are provided chelating agents particularly useful for the preparation of diagnostic and therapeutic agents for magnetic resonance imaging, scintigraphy, ultrasound imaging, radiotherapy and heavy metal detoxification, said agents being compounds of formula I wherein n and m are 2, 3 or 4; and A, X, R1 and Z are as defined in the specification.

Novel pesticides, preparation and use

The specification describes and claims methods of controlling acarine pests by application of a compound of Formula (I), methods of controlling arthropod pests by application of a compound of Formula (IA), compounds of Formula (IA) per se, pesticidal compositions comprising a compound of Formula (IA), and processes for preparing a compound of Formula (IA).

Synthesis and Use of 7-Substituted Norbornadienes for the Preparation of Prostaglandins and Prostanoids

Syntheses of 7-substituted norbornadienes from 7-t-butoxy- and 7-halogeno-norbornadienes are described.Rearrangement of the products in the presence of peracetic acid gives bicyclic aldehydes (2) in equilibrium with enol ethers (3) which are hydrolysed to hydroxycyclopentenylacetaldehydes (4), and converted into key intermediates for the synthesis of prostaglandins and their analogues.Syntheses of prostaglandin J analogues with n-hexyl and phenyl groups replacing the ο-side-chain are described.

Derivatives of C-6 functionalized 4-heteroalkanals. IV. Cyclic modifications in 6-hydroxy-4-oxa-alkanals

The synthesis of 6-hydroxy-4-oxa-hexanal, 6-hydroxy-4-oxa-heptanal and some derivatives of them are described.It is shown by combined spectroscopic and kinetic methods how these hydroxyaldehydes do not respond to equilibrium processes characteristic of simple 6-hydroxy-aldehydes, since a slow isomerization to the respective 2-(2-hydroxyethyl)-1,3-dioxolanes are observed on standing in CDCl3 solutions, whilst an equilibrium between the hydroxyaldehydes and their corresponding cyclohemiacetal forms are observed in dioxane-water 3/1.

Hydroboration. 57. Hydroboration with 9-Borabicyclononane of Alkenes Containing Representative Functional Groups

The hydroboration of alkenes containing representative functional groups was examined with 9-borabicyclononane (9-BBN) in order to extend the hydroboration reaction for the preparation of functionally substituted organoboranes.Terminal alkenes containing a remote functional group are hydroborated with a remarkable regioselectivity (>=98percent terminal), producing the corresponding stable organoboranes. 9-BBN hydroborates the allylic derivatives so as to place boron essentially on the terminal carbon atom (>=97percent).The directive effect is further enhanced (>=99percent) in the case of β-methylallyl derivatives.The hydroboration of crotyl derivatives attaches boron predominantly at the 2-position, followed by an elimination-rehydroboration sequence.However, crotyl alcohol can be protected against elimination as the tert-butyl or tetrahydropyranyl ethers.The hydroboration-oxidation of ethyl crotonate involves a series of elimination, hydroboration, and condensation processes.In the vinyl, crotyl, and isobutenyl systems, the mesomeric effect of the substituent favors the placement of boron at the β-position, while the inductive effect favors the α-position, with the former effect predominating in most cases.Acyclic β-substituted organoboranes undergo rapid elimination.Nonpolar solvents and lower reaction temperatures decrease the rate of elimination.However, those derived from cyclic vinyl derivatives are relatively stable under neutral conditions, undergoing facile elimination in the presence of a base.