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4-Ethoxycarbonyl-2-quinolone is a chemical compound with the molecular formula C12H9NO3. It is a derivative of quinolone, a class of heterocyclic compounds with a fused ring structure consisting of a benzene ring and a pyridine ring. This specific compound features an ethoxycarbonyl group (-COOCH2CH3) attached to the 4-position of the quinolone core. It is known for its potential applications in the synthesis of various pharmaceuticals and agrochemicals, particularly as a building block for the development of antimicrobial and antitumor agents. The compound's structure and properties make it a valuable intermediate in organic synthesis, allowing for further functionalization and the creation of more complex molecules with diverse biological activities.

5466-27-3

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5466-27-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 5466-27-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,4,6 and 6 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 5466-27:
(6*5)+(5*4)+(4*6)+(3*6)+(2*2)+(1*7)=103
103 % 10 = 3
So 5466-27-3 is a valid CAS Registry Number.
InChI:InChI=1/C12H11NO3/c1-2-16-12(15)9-7-11(14)13-10-6-4-3-5-8(9)10/h3-7H,2H2,1H3,(H,13,14)

5466-27-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name ethyl 2-oxo-1H-quinoline-4-carboxylate

1.2 Other means of identification

Product number -
Other names 2-Hydroxy-chinolin-4-carbonsaeure-ethylester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:5466-27-3 SDS

5466-27-3Relevant academic research and scientific papers

Microwave-assisted synthesis of quinoline derivatives from isatin

El Ashry, El Sayed H.,Ramadan, El Sayed,Hamid, Hamida Abdel,Hagar, Mohamed

, p. 2243 - 2250 (2007/10/03)

Microwave irradiation has been used for a rapid and efficient synthesis of quinoline-4-carboxylic acids 5a-g and 1,2,3,4-tetrahydroacridine-9-carboxylic acid (6) from the reaction of isatins 1-3 with acyclic and cyclic ketones in basic medium. 2-Hydroxyquinoline-4-carboxylic acid (11) was also obtained by irradiating a mixture of isatin 1 and malonic acid in AcOH. The esters of 5f and 11 and their respective hydrazides 8 and 13 were also prepared under MWI. Copyright Taylor & Francis, Inc.

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