54665-75-7Relevant academic research and scientific papers
Thionation of ω-acylamino ketones with Lawesson's reagent: Convenient synthesis of 1,3-thiazoles and 4H-1,3-thiazines
Nishio, Takehiko,Ori, Mayuko
, p. 2347 - 2354 (2007/10/03)
The reaction of ω-acylamino ketones with Lawesson's reagent (=2,4-bis(4-methoxyphenyl)-1,3,2,4-dithiadiphosphetane 2,4-disulfide; LR) is described. Treatment of 2-acylamino ketones 1 (n = 0) with LR gave 1,3-thiazole derivatives 3 in good yields (Scheme 1
Sulfur-containing heterocycles: Facile synthesis of 4H-1,3-thiazines by the reaction of 3-N-acylamino ketones with Lawesson's reagent
Ori, Mayuko,Nishio, Takehiko
, p. 111 - 116 (2007/10/03)
The treatment of 3-N-acylamino ketones with Lawesson's reagent [LR: 2,4- bis(p-methoxyphenyl)-1,3,2,4-dithiaphosphetane 2,4-disulfide] afforded the sulfur-containing heterocycles, 4H-1,3-thiazines in moderate to good yields, along with the corresponding 3-N-thioacylamino ketones.
