5468-56-4Relevant articles and documents
Efficient Palladium-Catalyzed Alkoxycarbonylation of Bulk Industrial Olefins Using Ferrocenyl Phosphine Ligands
Dong, Kaiwu,Sang, Rui,Fang, Xianjie,Franke, Robert,Spannenberg, Anke,Neumann, Helfried,Jackstell, Ralf,Beller, Matthias
supporting information, p. 5267 - 5271 (2017/04/27)
The development of ligands plays a key role and provides important innovations in homogeneous catalysis. In this context, we report a novel class of ferrocenyl phosphines for the alkoxycarbonylation of industrially important alkenes. A basic feature of our ligands is the combination of sterically hindered and amphoteric moieties on the P atoms, which leads to improved activity and productivity for alkoxycarbonylation reactions compared to the current industrial state-of-the-art ligand 1,2-bis((di-tert-butylphosphino)methyl)benzene). Advantageously, palladium catalysts with these novel ligands also enable such transformations without additional acid under milder reaction conditions. The practicability of the optimized ligand was demonstrated by preparation on >10 g scale and its use in palladium-catalyzed carbonylations on kilogram scale.
STEREOCHEMICALLY CONTROLLED SYNTHESIS OF RACEMIC SITOPHILATE, THE AGGREGATIONAL PHEROMONE OF THE GRAIN WEEVIL
Cheskis, B. A.,Moiseenkov, A. M.,Shpiro, N. A.,Stashina, G. A.,Zhulin, V. M.
, p. 716 - 720 (2007/10/02)
Controlled condensation of propionaldehyde with Li- or Si-enolates, generated from sec-amyl propionate, readily afforded a mixture of diastereomeric 2-methyl-3-hydroxypentanoic acid 3-pentyl esters, which were easily separated by chromatography.The erythr
