5470-46-2

Usage

InChI:InChI=1/C7H10N2O2/c1-7(4-2-3-4)5(10)8-6(11)9-7/h4H,2-3H2,1H3,(H2,8,9,10,11)

Upstream product

• 765-43-5 Cyclopropyl methyl ketone 
• 74-90-8 hydrogen cyanide 
• 124-38-9 carbon dioxide 
• 37024-73-0 2-amino-2-cyclopropyl-propanenitrile 
• 463-79-6 carbonic-acid 
• 151-50-8 potassium cyanide 

Downstream Products

• 5687-72-9 2-cyclopropylalanine 
• 95525-82-9 N²-acetyl-2-cyclopropylalanine 
• 95525-85-2 N²-<(S)-N²-acetyl-2-cyclopropylalanyl>-L-phenylalanine dimethylamide 
• 95525-83-0 N²-<(R)-N²-acetyl-2-cyclopropylalanyl>-L-phenylalanine dimethylamide 

Relevant academic research and scientific papers

AMIDOALKYLPIPERAZINYL DERIVATIVES FOR THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISEASES

The invention relates to novel amidoalkylpiperazinyl derivatives of tricyclic heterocyclic systems of general formula (I), wherein Z represents -NH- and X represents -S-, or Z represents -S- and X represents >C=C1 represents H or -CH3, R6 and R7 both represent H, n is an integer from 0 to 4 inclusive, G represents a cyclic amide or imide moiety, and optical isomers, geometric isomers, and pharmaceutically acceptable salts thereof. The compounds may be useful for the treatment and/or prevention of the central nervous system disorders.

Facile one-pot synthesis of 5-substituted hydantoins

5-Substituted and 5,5-disubstituted hydantoins are synthesised from the corresponding aldehydes or ketones, using a one-pot, gallium(iii) triflate-catalysed procedure that is compatible with a range of substrates and solvents.