54709-94-3

Basic information

• Product Name: 5-Methyl-3(2H)-pyridazinone
• Synonyms: 5-Methyl-3(2H)-pyridazinone;5-Methyl-2H-pyridazin-3-one;3-Hydroxy-5-methyl-pyridazine ;5-methylpyridazin-3(2H)-one;Nsc300284;3-Methyl-5,6-diaza-2,4-cyclohexadien-1-one;5-Methylpyrazinone;5-Methylpyridazin-3-ol
• CAS NO: 54709-94-3
• Molecular Formula: C5H6N2O
• Molecular Weight: 110.11
• Product Categories: Pyridazine series;Pyrazines, Pyrimidines & Pyridazines
• Mol File: 54709-94-3.mol
• Article Data: 11

Chemical Properties

• Melting Point: 151-153 °C
• Appearance: /
• Density: 1.22g/cm3
• Refractive Index: 1.576
• Storage Temp.: 2-8°C
• PKA: 11.50±0.40(Predicted)
• CAS DataBase Reference: 5-Methyl-3(2H)-pyridazinone(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Methyl-3(2H)-pyridazinone(54709-94-3)
• EPA Substance Registry System: 5-Methyl-3(2H)-pyridazinone(54709-94-3)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 54709-94-3(Hazardous Substances Data)

Usage

Description

5-Methyl-3(2H)-pyridazinone is a heterocyclic chemical compound characterized by a molecular formula of C5H6N2O. It features a pyridazine ring with a methyl group and a ketone functional group, making it a versatile building block in organic chemistry and pharmaceutical synthesis.

Uses

Used in Pharmaceutical Synthesis:
5-Methyl-3(2H)-pyridazinone is utilized as a key intermediate in the synthesis of various pharmaceuticals, contributing to the development of drugs for a range of medical conditions. Its unique structure allows for the creation of diverse medicinal compounds with potential therapeutic applications.
Used in Organic Chemistry:
As a heterocyclic compound, 5-Methyl-3(2H)-pyridazinone serves as a valuable starting material in organic chemistry, facilitating the production of other complex organic molecules. Its reactivity and functional groups make it suitable for a variety of chemical reactions and transformations.
Used in Drug Development:
5-Methyl-3(2H)-pyridazinone has been studied for its potential pharmacological properties, indicating its use in the development of new drugs. Its presence in various chemical structures may contribute to the discovery of novel therapeutic agents with improved efficacy and safety profiles.
Used in Chemical Production:
5-Methyl-3(2H)-pyridazinone may also be employed as an intermediate in the production of other chemicals, highlighting its importance in the chemical industry. Its versatility and reactivity make it a useful component in the synthesis of a wide array of chemical products.

InChI:InChI=1/C5H6N2O/c1-4-2-5(8)7-6-3-4/h2-3H,1H3,(H,7,8)

Upstream product

• 19064-64-3 3,6-dichloro-4-methylpyridazine 
• 89466-36-4 3-chloro-6-methoxy-4-methylpyridazine 
• 1173165-21-3 N'-acryloyl-4-methyl-N-(2-methylallyl)benzenesulfonohydrazide 
• 78920-07-7 γ-morpholinobutenolide 
• 40834-42-2 5-hydroxy-4-methyl-5H-furan-2-one 
• 83803-81-0 ethyl (E/Z)-4,4-dimethoxy-3-methylbut-2-enoate 
• 83297-15-8 5-(1,2-diaza-1-t-butyl-4-methylbutadien-4-ylidene)-2,2-dimethyl-1,3-dioxan-4,6-dione 
• 78920-13-5 2-ethoxy-3-methyl-2H-furan-5-one 
• 342402-51-1 5-methyl-3-oxo-2,3-dihydro-pyridazine-4-carboxylic acid 
• 1703-07-7 6-chloro-5-methyl-2H-pyridazin-3-one 

Downstream Products

• 1120-88-3 4-methylpyridazine 
• 89283-31-8 3-chloro-5-methylpyridazine 

Relevant articles and documents

Synthesis of substituted pyridines and pyridazines via ring closing metathesis

RCM can be used to make aromatic heterocycles, namely pyridines and, for the first time, pyridazines; the key step after RCM involves elimination of sulfinate to provide the aromatic system. The Royal Society of Chemistry 2009.

FUSED PYRROLIDINE 1,2,4-TRIAZOLE DERIVATIVES AS MODULATORS OF MGLUR5

The present invention is directed to novel compounds, to a process for their preparation, their use in therapy and pharmaceutical compositions comprising the novel compounds.

1,2,3-TRIAZOLE PYRROLIDINE DERIVATIVES AS MODULATORS OF MGLUR5

The present invention is directed to novel compounds, to a process for their preparation, their use in therapy and pharmaceutical compositions comprising the novel compounds.