5472-01-5

Basic information

• Product Name: 3-(4-bromophenyl)-1,3-diphenylpropan-1-one
• CAS NO: 5472-01-5
• Molecular Formula: C₂₁H₁₇BrO
• Molecular Weight: 365.2631
• Mol File: 5472-01-5.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 495.7°C at 760 mmHg
• Flash Point: 44.6°C
• Density: 1.312g/cm³
• Vapor Pressure: 5.78E-10mmHg at 25°C
• Refractive Index: 1.618
• CAS DataBase Reference: 3-(4-bromophenyl)-1,3-diphenylpropan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-bromophenyl)-1,3-diphenylpropan-1-one(5472-01-5)
• EPA Substance Registry System: 3-(4-bromophenyl)-1,3-diphenylpropan-1-one(5472-01-5)

Safety Data

• Hazardous Substances Data: 5472-01-5(Hazardous Substances Data)

Usage

General Description

3-(4-bromophenyl)-1,3-diphenylpropan-1-one, also known as 4'-bromo-α,α-diphenylacetophenone, is a chemical compound that belongs to the class of α-diketones. It consists of a central propanone group with two phenyl rings attached to it, as well as a bromine atom attached to one of the phenyl rings. 3-(4-bromophenyl)-1,3-diphenylpropan-1-one has potential applications in organic synthesis and pharmaceutical research due to its unique structure and reactivity. It may be used as a building block in the synthesis of various organic compounds, and its properties could be valuable for the development of new drugs or materials. Additionally, the bromine substitution may impart specific chemical and biological properties to the compound, making it potentially interesting for further investigation and study.

Upstream product

• 100-52-7 benzaldehyde 
• 98-86-2 acetophenone 
• 589-87-7 1,4-bromoiodobenzene 
• 94-41-7 benzalacetophenone 
• 90-90-4 (4-bromophenyl)(phenyl)methanone 
• 536-74-3 phenylacetylene 
• 29334-16-5 phenyl(4-bromophenyl)methanol 
• 614-20-0 3-oxo-3-phenylpropionic acid 
• 5467-74-3 4-Bromophenylboronic acid 
• 614-47-1 1,3-diphenyl-propen-3-one 
• 22966-09-2 (2E)-3-(4-bromophenyl)-1-phenylprop-2-en-1-one 
• 98-80-6 phenylboronic acid 
• 1200-07-3 trans-4-bromocinnamic acid 
• 71-43-2 benzene 

Relevant articles and documents

Stable and Reusable Palladium Nanoparticles-Catalyzed Conjugate Addition of Aryl Iodides to Enones: Route to Reductive Heck Products

An efficient, binaphthyl-backbone-stabilized palladium nanoparticles (Pd-BNP) catalyst for the 1,4-addition of aryl halides to enones has been developed. The scope of the reaction has been studied with various substituted and sterically hindered aryl hali

Decarboxylative substitution of β-keto acids to benzylic alcohols catalyzed by molecular iodine

An efficient method for molecular iodine catalyzed decarboxylative substitution of β-keto acids with benzylic alcohols under mild conditions has been described and valuable α-functionalized ketones were obtained in good to excellent yields.

Conjugate additions of α,β-unsaturated ketones with arylzinc species that form in situ from diethylzinc and arylboronic acids

Conjugate addition of α,β-unsaturated ketones with arylzinc species that form in situ from diethylzinc and a series of arylboronic acids by boron-zinc exchange reactions were investigated. 1,4-Addition products were formed in yields of 34-93%.