54724-82-2

Upstream product

• 127-65-1 chloroamine-T 
• 39078-08-5 rac-(3R,4R,5R,6R)-3,4:5,6-diepoxycyclohex-1-ene 
• 54724-79-7 3-Nitroso-6,9-bis(p-tolylsulfonyl)-(1α,2α,4α,5α,7α,8α)-3,6,9-triazatetracyclo<6.1.0.0^2,4.0^5,7>nonan 

Downstream Products

• 54724-84-4 1,4-Dihydro-1,4-bis(p-tolylsulfonyl)-1,4-diazocin 
• 112346-62-0 (1α,2α,4α,5α,7α,8α)-6,9-Bis(4-methylphenylsulfonyl)-3-oxa-6,9-diazatetracyclo<6.1.0.0^2,40^5,7>nonan 
• 112297-42-4 (1α,2β,4β,5α,7α,8α)-6,9-Bis(4-methylphenylsulfonyl)-3-oxa-6,9-diazatetracyclo<6.1.0.0^2,40^5,7>nonan 

Relevant academic research and scientific papers

cis,trans-Oxaaza-bis-?-homobenzenes - 4H-1,4-Oxazocines

The cis-oxaaza-bis-?-homobenzene framework has been synthesised via two routes starting from readily accessible materials (11, 25).As expected the N-SO2R derivatives 3a,b are sufficiently stable to be isolated; on heating, they readily and quantitatively undergo ?2 + ?2 + ?2>-cycloreversion to the 4H-1,4-oxazocines 6a,b (3b: t1/2(60 deg C) = 33.2 min; ΔG* = 104.0 kJ*mol-1).The latter prefer a non-planar, folded conformation.Using a precursor of 3b (27a), the thermally stable trans-oxaaza-bis-?-homobenzene 9 was obtained in very small yield (2 - 6percent) by two alternative pathways.

"cis-Diaza-bis-?-homobenzenes" (?2s + ?2s + ?2s>-Cycloreversion) - 1,4-Dihydro-1,4-diazocines ("Aromaticity")

Starting from "cis-benzene triimine" (3) the N,N'-disubstituted derivatives 8b-f are synthesized in 90-40percent yield.Nitrosation to the N-nitroso compounds 10b-f, spectroscopically identified below -30 deg C, and N2O-elimination lead to the c