39078-08-5Relevant articles and documents
Synthesis of novel mono and bis-indole conduritol derivatives and their α/β-glycosidase inhibitory effects
Cavdar, Hueseyin,Talaz, Oktay,Ekinci, Deniz
, p. 7499 - 7503 (2013/02/22)
Here we synthesized four novel indole conduritol derivatives 1-4 for the first time in the literature and probed their biological activities with the α and β-glucosidases. The compounds showed quite effective glucosidase inhibitory action. IC50
Synthesis of novel cyano-cyclitols and their stereoselective biotransformation catalyzed by Rhodococcus erythropolis A4
D'Antona, Nicola,Nicolosi, Giovanni,Morrone, Raffaele,Kubac, David,Kaplan, Ondrej,Martinkova, Ludmila
experimental part, p. 695 - 702 (2010/08/03)
A variety of novel cyano-cyclitols possessing complex stereochemistry have been synthesized. These compounds were subjected to the biocatalyzed hydrolysis of their nitrile groups. The bacterial strain Rhodococcus erythropolis A4, expressing a nitrile hydr
A novel chemo-multienzymatic synthesis of bioactive cyclophellitol and epi-cyclophellitol in both enantiopure forms
D'Antona, Nicola,Morrone, Raffaele,Bovicelli, Paolo,Gambera, Giovanni,Kubac, David,Martinkova, Ludmila
scheme or table, p. 2448 - 2454 (2011/02/22)
A new route to synthesize cyclophellitol and epi-cyclophellitol from racemic starting materials in enantiopure forms has been developed. The synthesis involves a multi-enzymatic biotransformation pathway of the novel cyano-cyclitol (1R,4S,5R,6R)/(1S,4R,5S
Concerning the reaction of anti-benzene dioxide with various nucleophiles
Esser, Thomas,Farkas, Frederic,Mangholz, Sissi,Sequin, Urs
, p. 3709 - 3720 (2007/10/02)
trans-3,4:5,6-Diepoxycyclohex-1-ene (anti-benzene dioxide) (5) was brought into reaction with several S, O, and C nucleophiles. S and O nucleophiles gave the bis-adducts stemming from independent reaction of the two epoxy functions. C nucleophiles, on the
cis-/trans--Trithia- and trans--Hexathia-tris-?-homobenzenes
Kagabu, Shinzo,Kaiser, Clemens,Keller, Reinhold,Becker, Paul G.,Mueller, Klaus-Helmuth,et. al.
, p. 741 - 756 (2007/10/02)
Starting from the cis- and trans-benzene trioxides 2/7 the cis-/trans--Trithia-tris-?-homobenzenes 1/6 and the trans-dioxathia-/oxadithia analogs 19/21 are synthesized by regioselective epoxide opening reactions with appropriate S-nucleophiles.Under the influence of heat and light cis-trisulfide 1 quickly looses sulfur and does not undergo ?2+?2+?2>cycloreversion.Attempts to build up cis--tris-?-homobenzenes from 2 by threefold six-membered ring anellation, in the special case of 1,2-benzenedithiol as 1,4-dinucleophil, led preferably to the trans--hexathia-tris-?-homobenzene 44 (X-ray analysis) manifesting effective S-neighbouring group participation. cis-Trisulfide 1 is a poor tridentate ligand: only with Ni(ClO4)2 a 2:1 complex (presumably octahedral, 48) is formed.