54737-66-5 Usage
Uses
Used in Pharmaceutical Industry:
2-(4-Phenoxyphenyl)propan-2-aMine is used as a potential antidepressant agent for its selective binding to the serotonin transporter, which has demonstrated antidepressant-like effects in animal models.
Used in Neurological Disorders Treatment:
2-(4-Phenoxyphenyl)propan-2-aMine is used as a potential therapeutic agent for the treatment of various neurological disorders due to its pharmacological properties and its interaction with the serotonin system.
Used in Drug Development:
2-(4-Phenoxyphenyl)propan-2-aMine is used as a ligand in the development of new drugs targeting the serotonin system, which may lead to the discovery of novel treatments for a range of conditions related to serotonin dysregulation.
Check Digit Verification of cas no
The CAS Registry Mumber 54737-66-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,4,7,3 and 7 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 54737-66:
(7*5)+(6*4)+(5*7)+(4*3)+(3*7)+(2*6)+(1*6)=145
145 % 10 = 5
So 54737-66-5 is a valid CAS Registry Number.
54737-66-5Relevant academic research and scientific papers
HETEROCYCLIC COMPOUNDS AS MUTANT IDH INHIBITORS
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Paragraph 0591; 0593, (2020/07/16)
The present disclosure relates generally to compounds useful in treatment of conditions associated with mutant isocitrate dehydrogenase (mt-IDH), particularly mutant IDH1 enzymes. Specifically, the present invention discloses compound of formula (IA), which exhibits inhibitory activity against mutant IDH1 enzymes. Method of treating conditions associated with excessive activity of mutant IDH1 enzymes with such compound is disclosed. Uses thereof, pharmaceutical composition, and kits are also disclosed.
Antiarrhythmic agents. 2, 3, and 4 substituted benzylamines
Remy,van Saun Jr.,Engelhardt
, p. 142 - 148 (2007/10/06)
The synthesis of a series of 2, 3, and 4 substituted benzylamine derivatives is described. These compounds were studied for their effect on experimental cardiac arrhythmias. Many of the derivatives, but in particular 2 (p methoxyphenylethynyl) benzylamine
