54752-30-6

Usage

General Description

1(2H)-Naphthalenone, 3,4-dihydro-2-[(4-methylphenyl)methylene]- is a chemical compound with the molecular formula C18H16O. It is a yellow crystalline solid that is commonly used in the production of pharmaceuticals, dyestuffs, and fragrance compounds. This chemical compound may also have potential applications in the field of organic synthesis and medicinal chemistry due to its unique structure and properties. Additionally, it is important to handle 1(2H)-Naphthalenone, 3,4-dihydro-2-[(4-methylphenyl)methylene]- with caution and follow proper safety protocols, as it may pose certain health risks if not handled properly.

Upstream product

• 104-87-0 4-methyl-benzaldehyde 
• 529-34-0 3,4-dihydronaphthalene-1(2H)-one 

Downstream Products

• 157282-75-2 4-(4-methylphenyl)-3,4,5,6-tetrahydro-1H-benzo[h]quinazolin-2-thione 
• 1227624-17-0 8-methoxy-3-(1-(4-methylphenyl)-9,10-dihydro-4-azaphenanthren-3-yl)coumarin 
• 1227624-12-5 3-[1-(4-methylphenyl)-9,10-dihydro-4-azaphenanthren-3-yl]coumarin 
• 1227624-22-7 2-[1-(4-methylphenyl)-9,10-dihydro-4-azaphenanthren-3-yl]benzo[f]coumarin 
• 1379762-78-3 (2R,3'S)-3'-(4-methphenyl)-3,4-dihydro-1H-spiro[naphthalene-2,2'-oxiran]-1-one 

Relevant academic research and scientific papers

Selectivity in the Aerobic Dearomatization of Phenols: Total Synthesis of Dehydronornuciferine by Chemo- and Regioselective Oxidation

We describe a selective aerobic oxidation of meta-biaryl phenols that enables rapid access to functionalized phenanthrenes. Aerobic oxidations attract interest due to their efficiency, but remain underutilized in complex molecule settings due to challenge

Synthesis, characterization, and investigations of antimicrobial activity of 6,6-dimethyl-3-aryl-3′,4′,6,7-tetrahydro-1′H,3H-spiro[benzofuran-2,2′-naphthalene]-1′,4(5H)-dione

Chalcone-like compounds 3a–l, 2-(benzylidene)-3,4-dihydronaphthalen-1(2H)-one, were synthesized from the addition of different benzaldehyde derivatives (2a–l) to 1,2,3,4-tetrahydro-1-napthalone (1) in basic medium. Mn(OAc)3-mediated addition of

Antibacterial and antitubercular evaluation of dihydronaphthalenone-indole hybrid analogs

A new series of indole appended dihydronaphthalenone hybrid analogs (5a–t) have been synthesized through the Lewis acid catalyzed Michael addition of indoles to the arylidene/hetero arylidene ketones. All the synthesized derivatives are well characterized

Discovery of 3,3a,4,5-tetrahydro-2H-benzo[g]indazole containing quinoxaline derivatives as novel EGFR/HER-2 dual inhibitors

In the present study, twenty-five pyrazole-quinoxaline derivatives (4a-4y) were designed and synthesized, and their biological activity as potential EGFR or HER-2 kinase inhibitors was evaluated. Among them, compound 4l displayed better antiproliferative

UV-light induced domino type reactions: Synthesis and photophysical properties of unreported nitrogen ring junction quinazolines

An expedient method for the synthesis of 5,6-dihydrobenzo[h][1,2,4]triazolo[5,1-b]quinazolines by UV light has been developed. Our aim was to synthesize various α, β-unsaturated carbonyl compounds and to further react them with different amines in DMF, in

Modified Pyridine-Substituted Coumarins: A New Class of Antimicrobial and Antitubercular Agents

Some new biologically potent coumarin derivatives 7a-f, 8a-f, and 9a-f bearing modified pyridine moieties (indeno[1,2-b]pyridine, 4-azaphenanthrene and benzofuro [3,2-b]pyridine) at the sixth position were designed and synthesized. All the synthesized com

Fused Heterocycles: Part III - Attempted Synthesis of 4,5-Dihydro-3-arylnaphthisoxazoles

2-Benzal-1-tetralone dibromide (II), obtained by the bromination of 2-benzal-1-tetralone, on treatment with hydroxylamine hydrochloride in the presence of alc.KOH undergoes cyclization to the unexpected product 3,3a,4,5-tetrahydro-3-arylnaphthisoxa