54788-19-1Relevant articles and documents
Methylene versus carbonyl bridge in the structure of new tubulin polymerization inhibitors with tricyclic A-rings
Moise, Iuliana-Monica,B?cu, Elena,Dubois, Jo?lle,Farce, Amaury,Rigo, Beno?t,Ghinet, Alina
, p. 6021 - 6030 (2016/11/09)
The phenothiazine group has been identified as a suitable A ring in the structure of tubulin polymerization inhibitors. In our search to identify more potent inhibitors, a study of different isosteric tricyclic groups as new potential A rings was first re
1-SUBSTITUTED-3- BETA-D-GLUCOPYRANOSYLATED NITROGENOUS HETERO- CYCLIC COMPOUNDS AND MEDICINES CONTAINING THE SAME
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Page/Page column 23, (2008/06/13)
A compound having an SGLT1 and/or SGLT2 inhibitory activity which is usable as an agent for the prevention or treatment of diabetes, postprandial hyperglycemia, impaired glucose tolerance, diabetic complications, obesity, etc. It is a 1-substituted-3-(β-D
Asymmetric synthesis of fluorinated L-tyrosine and meta-L-tyrosines
Monclus, Michel,Masson, Carine,Luxen, Andre
, p. 39 - 44 (2007/10/02)
A convenient asymmetric synthesis of (2S)-2-amino-3-(2-fluoro-5-hydroxyphenyl) propanoic acid, (2S)-2-amino-3-(4-fluoro-3-hydroxyphenyl) propanoic acid and (2S)-2-amino-3-(2-fluoro-4-hydroxyphenyl) propanoic acid is described.Key steps include the synthes