54788-29-3

Upstream product

• 405-06-1 2-fluoro-4-methoxy-1-methylbenzene 
• 331-63-5 1-(chloromethyl)-2-fluoro-4-methoxybenzene 
• 428-81-9 acetylamino-(2-fluoro-4-methoxy-benzyl)-malonic acid diethyl ester 
• 349-18-8 N-acetyl-2-fluoro-O-methyl-tyrosine 
• 321-24-4 2-Fluor-4-methoxybenzoesaurechlorid 

Downstream Products

• 7656-31-7 o-fluoro-DL-tyrosine 

Relevant academic research and scientific papers

METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE

The present invention provides methods of efficiently producing various optically active aromatic amino acid derivatives by reacting, using an additive, a specific ester compound with an aromatic halide and zinc in the presence of a catalyst. The present invention also provides amino acid derivatives that can be produced by the methods.

COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS

The present invention is directed to therapeutic compounds which have dual activity as agonists of GPR119 and inhibitors of DPP-IV and are useful for the treatment of metabolic disorders including type II diabetes.

Synthesis and microbiological activities of some monohalogenated analogs of tyrosine

2 Chlorotyrosine and 2 bromotyrosine, as well as the previously reported 2 fluorotyrosine, were synthesized by hydrolysis of the condensation products from the appropriate benzyl bromide and ethyl acetamidomalonate and were compared with the corresponding