54796-47-3

Basic information

• Product Name: METHYL 5-BROMO-4-METHYL-2-THIOPHENECARBOXYLATE
• Synonyms: METHYL 5-BROMO-4-METHYL-2-THIOPHENECARBOXYLATE;Methyl 5-bromo-4-methylthiophene-2-carboxylate;5-Bromo-2-(methoxycarbonyl)-4-methylthiophene;5-Bromo-2-(methoxycarbonyl)-4-methylthiophene, Methyl 5-bromo-4-methyl-2-thenoate
• CAS NO: 54796-47-3
• Molecular Formula: C₇H₇BrO₂S
• Molecular Weight: 235.1
• Mol File: 54796-47-3.mol
• Article Data: 4

Chemical Properties

• Melting Point: 35 °C
• Boiling Point: 275.6 °C at 760 mmHg
• Flash Point: 120.5 °C
• Appearance: /
• Density: 1.575 g/cm³
• Vapor Pressure: 0.00505mmHg at 25°C
• Refractive Index: 1.569
• CAS DataBase Reference: METHYL 5-BROMO-4-METHYL-2-THIOPHENECARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 5-BROMO-4-METHYL-2-THIOPHENECARBOXYLATE(54796-47-3)
• EPA Substance Registry System: METHYL 5-BROMO-4-METHYL-2-THIOPHENECARBOXYLATE(54796-47-3)

Safety Data

• Hazard Codes: Xi
• Statements: R36/37/38:Irritating to eyes, respiratory system and skin.
• Safety Statements: S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.; S37/39:Wear suitable g
• Hazardous Substances Data: 54796-47-3(Hazardous Substances Data)

Usage

General Description

METHYL 5-BROMO-4-METHYL-2-THIOPHENECARBOXYLATE is a chemical compound with the molecular formula C10H9BrO2S. It is a yellow to brown liquid with a sulfurous odor. METHYL 5-BROMO-4-METHYL-2-THIOPHENECARBOXYLATE is commonly used in the pharmaceutical and agrochemical industries as an intermediate for the synthesis of various pharmaceuticals and agrochemicals. It is also used in organic synthesis as a reagent for the preparation of other organic compounds. METHYL 5-BROMO-4-METHYL-2-THIOPHENECARBOXYLATE is known for its versatility and wide range of applications in the chemical industry.

InChI:InChI=1/C7H7BrO2S/c1-4-3-5(7(9)10-2)11-6(4)8/h3H,1-2H3

Upstream product

• 54796-53-1 5-Bromo-4-methyl-thiophene-2-carboxylic acid 
• 74-88-4 methyl iodide 
• 14282-78-1 4-methylthiophene-2-carboxylic acid 
• 28686-90-0 4-methyl-thiophene-2-carboxylic acid methyl ester 
• 67-56-1 methanol 

Downstream Products

• 189330-08-3 5-bromo-4-methyl-2-thiophenecarboxamide 
• 1417798-36-7 methyl-5-(4-methoxyphenyl)-4-methylthiophene-2-carboxylate 
• 917022-83-4 5-[4-(1-ethyl-1-{4-[5-(1-ethyl-1-hydroxypropyl)-3-methyl-thiophen-2-yl]-3-methyl-phenyl}-propyl)-2-methyl-phenoxy]-4(R)-hydroxy-pentanoic acid 
• 917024-78-3 5-(4-{1-[4-(t-butyl-dimethyl-silanyloxy)-3-methyl-phenyl]-1-ethyl-propyl}-2-methyl-phenyl)-4-methyl-thiophene-2-carboxylic acid methyl ester 
• 1374131-11-9 methyl 5-{3-[6-azetidin-1-yl-2-({(4S,5R)-5-[3,5-bis(trifluoromethyl)phenyl]-4-methyl-2-oxo-1,3-oxazolidin-3-yl}methyl)pyridin-3-yl]-4-methoxyphenyl}-4-methylthiophene-2-carboxylate 
• 1239577-12-8 methyl 4-methyl-5-[1-(phenylmethyl)-1H-pyrazol-4-yl]-2-thiophenecarboxylate 
• 917024-77-2 5-{4-[1-ethyl-1-(4-hydroxy-3-methyl-phenyl)-propyl]-2-methyl-phenyl}-4-methyl-thiophene-2-carboxylic acid methyl ester 
• 946426-96-6 5-(4-methoxy-2-methyl-phenyl)-4-methyl-thiophene-2-carboxylic acid methyl ester 
• 28686-90-0 4-methyl-thiophene-2-carboxylic acid methyl ester 
• 54796-53-1 5-Bromo-4-methyl-thiophene-2-carboxylic acid 

Relevant articles and documents

THIOPHENE, MANUFACTURING METHOD THEREOF, AND PHARMACEUTICAL APPLICATION OF SAME

The present invention discloses a thiophene used as a uric acid transporter (URAT1) inhibitor and applicantion of the thiophene in preparing a pharmaceutical product for treating a disease related to abnormal uric acid levels, specifically in preparing a pharmaceutical product for treating hyperuricemia and gouty arthritis. The invention specifically relates to a compound as represented by formula (I) or a pharmaceutically acceptable salt thereof.

Phosphorylamides, their preparation and use

A phosphorylamide derivative represented by the general formula (I): STR1 wherein R represents an amino group that may be substituted, or a salt thereof, possesses potent antibacterial activity against Helicobacter bacterium, especially Helicobacter pylori, and is useful for prevention or treatment of digestive diseases caused by Helicobacter bacterium, solely or in combination with an antacid or an acid secretion inhibitor.