54796-47-3

Usage

Uses

Used in Pharmaceutical Industry:
METHYL 5-BROMO-4-METHYL-2-THIOPHENECARBOXYLATE is utilized as an intermediate in the synthesis of various pharmaceuticals. Its unique chemical structure allows it to be a key component in the development of new drugs, contributing to the advancement of medical treatments.
Used in Agrochemical Industry:
In the agrochemical sector, METHYL 5-BROMO-4-METHYL-2-THIOPHENECARBOXYLATE serves as an intermediate for the production of agrochemicals. Its role in this industry is crucial for the creation of effective pesticides and other agricultural chemicals that protect crops and enhance agricultural productivity.
Used in Organic Synthesis:
METHYL 5-BROMO-4-METHYL-2-THIOPHENECARBOXYLATE is also employed as a reagent in organic synthesis. It is instrumental in the preparation of other organic compounds, expanding the scope of chemical research and development, and contributing to the discovery of novel chemical entities with potential applications across various industries.

InChI:InChI=1/C7H7BrO2S/c1-4-3-5(7(9)10-2)11-6(4)8/h3H,1-2H3

Upstream product

• 54796-53-1 5-Bromo-4-methyl-thiophene-2-carboxylic acid 
• 67-56-1 methanol 
• 28686-90-0 4-methyl-thiophene-2-carboxylic acid methyl ester 
• 14282-78-1 4-methylthiophene-2-carboxylic acid 
• 74-88-4 methyl iodide 

Downstream Products

• 28686-90-0 4-methyl-thiophene-2-carboxylic acid methyl ester 
• 1417798-36-7 methyl-5-(4-methoxyphenyl)-4-methylthiophene-2-carboxylate 
• 917022-83-4 5-[4-(1-ethyl-1-{4-[5-(1-ethyl-1-hydroxypropyl)-3-methyl-thiophen-2-yl]-3-methyl-phenyl}-propyl)-2-methyl-phenoxy]-4(R)-hydroxy-pentanoic acid 
• 917024-78-3 5-(4-{1-[4-(t-butyl-dimethyl-silanyloxy)-3-methyl-phenyl]-1-ethyl-propyl}-2-methyl-phenyl)-4-methyl-thiophene-2-carboxylic acid methyl ester 
• 1374131-11-9 methyl 5-{3-[6-azetidin-1-yl-2-({(4S,5R)-5-[3,5-bis(trifluoromethyl)phenyl]-4-methyl-2-oxo-1,3-oxazolidin-3-yl}methyl)pyridin-3-yl]-4-methoxyphenyl}-4-methylthiophene-2-carboxylate 
• 1239577-12-8 methyl 4-methyl-5-[1-(phenylmethyl)-1H-pyrazol-4-yl]-2-thiophenecarboxylate 
• 917024-77-2 5-{4-[1-ethyl-1-(4-hydroxy-3-methyl-phenyl)-propyl]-2-methyl-phenyl}-4-methyl-thiophene-2-carboxylic acid methyl ester 
• 946426-96-6 5-(4-methoxy-2-methyl-phenyl)-4-methyl-thiophene-2-carboxylic acid methyl ester 
• 189330-08-3 5-bromo-4-methyl-2-thiophenecarboxamide 
• 54796-53-1 5-Bromo-4-methyl-thiophene-2-carboxylic acid 

Relevant academic research and scientific papers

THIOPHENE, MANUFACTURING METHOD THEREOF, AND PHARMACEUTICAL APPLICATION OF SAME

The present invention discloses a thiophene used as a uric acid transporter (URAT1) inhibitor and applicantion of the thiophene in preparing a pharmaceutical product for treating a disease related to abnormal uric acid levels, specifically in preparing a pharmaceutical product for treating hyperuricemia and gouty arthritis. The invention specifically relates to a compound as represented by formula (I) or a pharmaceutically acceptable salt thereof.

LST-1 and/or LST-2 transported by compd.

PROBLEM TO BE SOLVED: To provide a new probe for cancer cell detection or hepatic cell detection and a medicament carrier comprising the compound and delivering a medicament to a cancer cell or a hepatic cell.SOLUTION: A new transport substrate for LST-1

Phosphorylamides, their preparation and use

A phosphorylamide derivative represented by the general formula (I): STR1 wherein R represents an amino group that may be substituted, or a salt thereof, possesses potent antibacterial activity against Helicobacter bacterium, especially Helicobacter pylori, and is useful for prevention or treatment of digestive diseases caused by Helicobacter bacterium, solely or in combination with an antacid or an acid secretion inhibitor.

Compounds useful as antiproliferative agents and GARFT inhibitors

Compounds of the Formula I, which are in equilibrium with their 4-hydroxy tautomers and are in the form of diastereomeric mixtures, and their pharmaceutically acceptable salts are potent GARFT inhibitors: STR1 wherein A, Z, X, and R1 and R2 are defined in the specification. These compounds and their salts are useful as antiproliferative agents. The invention also pertains to pharmaceutical compositions and methods employing such compounds as GARFT inhibitors or antiproliferative agents. The invention also relates to compounds useful as intermediates for preparing such compounds, and to their synthesis.