54796-53-1

Usage

Uses

Used in Pharmaceutical Synthesis:
5-Bromo-4-methylthiophene-2-carboxylic acid is used as a key intermediate in the synthesis of pharmaceuticals for its potential biological activity. The presence of the bromine atom and the carboxylic acid group allows for further chemical modifications, making it a versatile building block in the development of new drugs with improved therapeutic properties.
Used in Agrochemical Development:
In the agrochemical industry, 5-Bromo-4-methylthiophene-2-carboxylic acid is utilized as a precursor in the synthesis of various agrochemicals. Its unique structure and functional groups contribute to the creation of compounds with specific pesticidal or herbicidal properties, enhancing crop protection and yield.
Used in Organic Synthesis:
5-Bromo-4-methylthiophene-2-carboxylic acid serves as a valuable building block in organic synthesis, particularly in the development of new materials and pharmaceuticals. Its reactivity and structural features facilitate the synthesis of complex organic molecules, broadening the scope of chemical research and innovation.
Used in Material Science:
In the field of material science, 5-Bromo-4-methylthiophene-2-carboxylic acid is employed in the design and synthesis of novel materials with specific properties. Its incorporation into polymers or other materials can lead to the development of materials with enhanced stability, conductivity, or other desirable characteristics for various applications.
Overall, 5-Bromo-4-methylthiophene-2-carboxylic acid is a versatile chemical compound with a wide range of applications across different industries, including pharmaceuticals, agrochemicals, organic synthesis, and material science, due to its unique structure and functional groups.

InChI:InChI=1/C6H5BrO2S/c1-3-2-4(6(8)9)10-5(3)7/h2H,1H3,(H,8,9)

Upstream product

• 14282-78-1 4-methylthiophene-2-carboxylic acid 
• 54796-47-3 5-bromo-4-methyl-2-thiophenecarboxylic acid methyl ester 
• 14282-76-9 2-bromo-3-methylthiophene 
• 7758-19-2 sodium chlorite 
• 189331-47-3 5-bromo-4-methyl-2-thiophene carboxaldehyde 
• 4885-02-3 Dichloromethyl methyl ether 

Downstream Products

• 54796-47-3 5-bromo-4-methyl-2-thiophenecarboxylic acid methyl ester 

Relevant academic research and scientific papers

Novel ASK1 inhibitor and application thereof

The invention relates to a compound shown as a general formula (I), a pharmacologically acceptable salt, ester or a stereisomer. The invention also relates to a preparation method of the compound, a medicine preparation containing the compound and a medic

Useful thiophene derivatives in the treatment of diabetes

The present invention relates to a thiophene derivative of the following general formula I or an enantiomer, diastereoisomer, hydrate, solvate, tautomer, racemic mixture or pharmaceutically acceptable salt thereof or to its use as a drug in particular intended for treating and/or preventing diabetes, its complications and/or associated pathologies, advantageously diabetes of type II and hyperglycemia.

USEFUL THIOPHENE DERIVATIVES IN THE TREATMENT OF DIABETES

The present invention relates to a thiophene derivative of the following general formula I or an enantiomer, diastereoisomer, hydrate, solvate, tautomer, racemic mixture or pharmaceutically acceptable salt thereof or to its use as a drug in particular intended for treating and/or preventing diabetes, its complications and/or associated pathologies, advantageously diabetes of type II and hyperglycemia.

Stereoselective process for the synthesis of chiral garft compounds and intermediates

The present invention describes a stereoselective preparation of derivatives and precursors of molecules having formula 1: Method of preparing the compounds, intermediates and derivatives are described. The methods described herein allow the preparation o

CYSTEINE PROTEASE INHIBITORS

A compound of the formula (II) wherein one of R1 and R2 is halo and the other is H or halo; R3 is C1-C4 straight or branched chain, optionally fluorinated, alkyl; R4 is H; or R3 together with R4 and the adjoining backbone carbon defines: a spiro-C5-C7 cycloalkyl, optionally substituted with 1 to 3 substituents selected from halo, hydroxyl, C1-C4 alkyl or C1-C4 haloalkyl; or optionally bridged with a methylene group; or a C4-C6 saturated heterocycle having a hetero atom selected from O, NRa, S, S(=O)2 ; where Ra is H, C1-C4 alkyl or CH3C(=O); R5 is independently selected from H or methyl; E is -C(=O)-, -S(=O)m-, -NR5S(=O)m-, -NR5C(=O)-, -OC(=O)-, R6 is a stable, optionally substituted, monocyclic or bicyclic, carbocycle or hetorocycle; m is independently 0,1 or 2; are inhibitors of cathepsin K and useful in the treatment or prophylaxis of osteoporosis.

Phosphorylamides, their preparation and use

A phosphorylamide derivative represented by the general formula (I): STR1 wherein R represents an amino group that may be substituted, or a salt thereof, possesses potent antibacterial activity against Helicobacter bacterium, especially Helicobacter pylori, and is useful for prevention or treatment of digestive diseases caused by Helicobacter bacterium, solely or in combination with an antacid or an acid secretion inhibitor.