54813-93-3Relevant academic research and scientific papers
DERIVATIVES OF 2-PYRIDIN-2-YL-PYRAZOL-3(2H)-ONE, PREPARATION AND THERAPEUTIC USE THEREOF AS HIF ACTIVATORS
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Page/Page column 23, (2011/12/13)
The present invention relates to novel substituted dihydropyrazolone derivatives, to their preparation and to their therapeutic use as activators of the transcription factor HIF.
Chemo-Enzymatic Method for the Synthesis of Statine, Phenylstatine and Analogues
Kambourakis, Spiros,Rozzell, J. David
, p. 699 - 705 (2007/10/03)
A chemo-enzymatic method for the synthesis of statine [(3S,4R)-4-amino-3- hydroxy-6-methylheptanoic acid] and statine analogues with natural and unnatural side chains is described. The key step of the synthesis is the diastereoselective reduction of a 2-a
