2-Benzyl-3-ketoglutarate diethyl ester

Base Information

Chemical Name:2-Benzyl-3-ketoglutarate diethyl ester
CAS No.:54813-93-3
Molecular Formula:C16H20O5
Molecular Weight:292.332
Hs Code.:
DSSTox Substance ID:DTXSID60480147

Synonyms:2-benzyl-3-ketoglutarate diethyl ester;54813-93-3;SCHEMBL5141896;DTXSID60480147;HZOCADZQLFGJLU-UHFFFAOYSA-N

Suppliers and Price of 2-Benzyl-3-ketoglutarate diethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 5 raw suppliers

Chemical Property of 2-Benzyl-3-ketoglutarate diethyl ester

Chemical Property:

XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:10
Exact Mass:292.13107373
Heavy Atom Count:21
Complexity:358

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC(=O)CC(=O)C(CC1=CC=CC=C1)C(=O)OCC

Technology Process of 2-Benzyl-3-ketoglutarate diethyl ester

There total 2 articles about 2-Benzyl-3-ketoglutarate diethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.0%

: 100-39-0
benzyl bromide

: 105-50-0
diethyl 1,3-acetonedicarboxylate

: 54813-93-3
diethyl 2-benzyl-3-ketoglutarate

Guidance literature:: With sodium; In ethanol; at 20 ℃; for 3h; Inert atmosphere; Reflux;

Reference yield:

: 463-51-4
Ketene

: 29425-06-7
benzylmalonyl dichloride

: 54813-93-3
diethyl 2-benzyl-3-ketoglutarate

Guidance literature:: With chloroform; anschliessend Behandeln mit Aethanol;

Reference yield:

: 54813-93-3
diethyl 2-benzyl-3-ketoglutarate

: 651735-57-8
diethyl (2R,3R)-2-benzyl-3-hydroxyglutarate

Guidance literature:: With D-glucose; NADPH; sodium chloride; lyophilized glucose dehydrogenase; NADPH-dependent ketoreductase KRED-108; In phosphate buffer; dimethyl sulfoxide; at 37 ℃; pH=6.5; Enzymatic reaction;