54863-62-6

Usage

InChI:InChI=1/C11H24O2S/c1-3-4-5-6-7-8-9-10-11-14(2,12)13/h3-11H2,1-2H3

Upstream product

• 74-88-4 methyl iodide 
• 22438-39-7 1-(methylthio)decane 
• 71053-04-8 2-n-hexyl sulfolane 
• 142023-36-7 4-(Decane-1-sulfonyl)-pyridine 
• 142023-35-6 2-(Decane-1-sulfonyl)-pyridine 
• 142023-37-8 2-(Decane-1-sulfonyl)-pyrimidine 
• 616-42-2 dimethylsulfite 
• 2050-77-3 Iododecane 

Relevant academic research and scientific papers

Preparation method of methyl sulfone compound

The invention discloses a synthesis method of a methyl sulfone compound, which comprises the following steps: by using an iodinated compound as a substrate, adding a sulfite compound into the substrate, and using a 1, 4-dioxane solution as a solvent, heating under the protection of nitrogen under the actions of a silicon reagent, a phase transfer catalyst and a palladium catalyst to obtain a crudeproduct; then purifying the crude product, firstly filtering the crude product, and removing the solvent to obtain residues; carrying out silica gel column chromatography on the residues, leaching with eluent, and collecting effluent; combining the effluent containing the product; and concentrating the combined effluent to remove the solvent, and finally carrying out vacuum drying to obtain the target product. The method has the advantages of simple process flow, easiness in product purification, environmental safety and high yield.

Sulfone compound (by machine translation)

[Problem] to safely and conveniently, highly selective, sulfide compound producing a sulfone compound. [Solution] pH is 9 - 12 under, water or water-insoluble solvent or an aromatic hydrocarbon-based solvent mixture, sodium hypochlorite is used as oxidizing agent, (1) (2) from the compound represented by the formula sulfide sulfone compound represented by the formula manufacturing method. (R1 And R2 Are each independently an alkyl, aryl, aralkyl, heteroaryl)[Drawing] no (by machine translation)

Optimization of asymmetric oxidation of sulfides with the Fe(salan) complex in water and the expanded scope of its application

The scope of asymmetric oxidation of sulfides using Fe(salan) complex as a catalyst and aqueous hydrogen peroxide as an oxidant in water was broadened by optimizing the reaction conditions with respect to reaction temperature, catalyst loading, and amount of water solvent. The oxidation proceeded with high enantioselectivity under the optimized conditions. The undesired over-oxidation of the resultant sulfoxides was significantly suppressed and the yields of sulfoxides were improved. Various functional groups were tolerant of the conditions.

The first example of direct oxidation of sulfides to sulfones by an osmate molecular oxygen system

Osmate-exchanged Mg-Al layered double hydroxides catalysed the delivery of two oxygen atoms simultaneously via a 3 + 1 cycloaddition to sulfide to form sulfone directly for the first time, reminiscent of 3 + 2 cycloaddition in asymmetric dihydroxylation reactions.

Cathodic cleavage of heteroarylalkylsulfones: A facile route to long chain aliphatic sulfinates and relevant sulfones

Heteroarylalkylsulfones - mainly pyridylalkylsulfones - exhibit a cathodic cleavage reaction producing alkanesulfinate anion in high yield. This reaction is tested with long chain alkyl groups and allows an easy synthesis of aliphatic sulfinic acids.

Selective Autoxidation of Electron-Rich Substrates under Elevated Oxygen Pressures

We report here the observation of a novel autoxidation pathway which occurs with electron-rich substrates.Tertiary amines, dialkyl thioethers, olefins, and alkynes under high oxygen pressures (>20 bars of O2), in polar solvents, and at elevated temperatures (>90 deg C) yield in good to excellent selectivity amine oxides, sulfoxides, and site-specific olefin and alkyne cleavage products, respectively.The results of mechanistic studies, including high oxygen pressure electrochemical studies, are discussed.A mechanism for this novel oxygenation reaction pathway that is consistent with the observed results is proposed.It involves an initial unfavorable electron transfer from the electron-rich substrate to oxygen to yield superoxide and the radical cation, which reacts with triplet oxygen to yield the oxygenated radical cation intermediate, a suspected potent oxidant.Electron transfer to the oxygenated radical cation from additional substrate (chain reaction) or superoxide yields a zwitterionic intermediate.This intermediate either reacts with additional substrate (O-atom transfer) to yield product (sulfoxide and N-oxide, in the case of thioethers and tertiary amines) or is converted with unimolecular reactivity to dioxetane-like (in the case of alkenes) or dioxetene-like (in the case alkynes) derived products.

The Novel Cerium(IV)-catalysed Molecular Oxygen Oxidation of Thioethers to Sulphoxides

Thioethers can be oxidized with catalytic amounts of Ce(IV) salts rapidly and selectively to sulphoxides using molecular oxygen (PO2 = 5-15 bar) as the oxidant.

CONVENIENT DESULFONYLATION REACTIONS OF CYCLIC SULFONES WITH ULTRASONICALLY DISPERSED POTASSIUM

Ultrasonically dispersed potassium, generated in toluene with an ultrasonic cleaning bath, was found to be efficient and regioselective for desulfonylation of cyclic sulfones.

Mechanistic Studies of the Selective Oxygen Oxidation of Sulfides to Sulfoxides Catalyzed by Dihaloruthenium(II) Complexes

The selective and facile molecular oxygen oxidation of dialkyl sulfides to their sulfoxides can be effectively catalyzed by neutral ruthenium(II) complexes of the type cis- or trans-RuX2(Me2SO)4.The results of kinetic studies for two of these catalysts, cis-RuCl2(Me2SO)4 and trans-RuBr2(Me2SO)4, show that these catalytic oxidations are first order with respect to total catalyst concentration, less than first order in oxygen concentration, zero order in the sulfide substrate, and approximately first order in alcohol.These and other observations plus 18O-labeling studies support a mechanism involving oxidation of a "Ru(II)" species to give an oxidized metal species, probably "Ru(IV)" and peroxide.The active sulfide oxidant is peroxide, whose concentration is approximated by the steady-state assumption.The reductant of the oxidized metal is the solvent alcohol, thus completing the catalytic cycle.