54864-78-7

Usage

Uses

Used in Agrochemical Industry:
3-(HEPTAFLUORO-1-PROPYL)-5-PHENYLPYRAZOLE is used as an active ingredient in the production of insecticides and agrochemicals for its pesticidal activity. It functions as an inhibitor of the enzyme acetylcholinesterase, which plays a crucial role in the transmission of nerve impulses in insects. By inhibiting this enzyme, the compound leads to paralysis and death of the insects, making it an effective tool in pest control.
Used as a Pyrethroid Synergist:
3-(HEPTAFLUORO-1-PROPYL)-5-PHENYLPYRAZOLE has been studied for its potential as a pyrethroid synergist, enhancing the effectiveness of other insecticides. Its ability to work in conjunction with pyrethroids can improve the overall efficacy of insecticide treatments, particularly in cases where pests have developed resistance to standard insecticides. This makes it a valuable compound in the development of more effective and sustainable pest management strategies in agriculture and other related fields.

InChI:InChI=1/C12H7F7N2/c13-10(14,11(15,16)12(17,18)19)9-6-8(20-21-9)7-4-2-1-3-5-7/h1-6H,(H,20,21)

Upstream product

• 53580-21-5 4,4,5,5,6,6,6-heptafluoro-1-phenyl-hexane-1,3-dione 
• 66249-23-8 3,3,4,4,5,5,6,6,6-Nonafluoro-1-phenyl-1-hexyne 
• 98-86-2 acetophenone 
• 423-39-2 1-iodo-2,2,3,3,4,4,5,5,5-nonafluorobutane 
• 618-34-8 1-chlorostyrene 

Downstream Products

• 75823-94-8 3-(3-Heptafluoropropyl-5-phenyl-pyrazol-1-yl)-propionitrile 
• 82633-52-1 4-Bromo-3-heptafluoropropyl-5-phenyl-1H-pyrazole 
• 75823-73-3 5-(heptafluoropropyl)-1-methyl-3-phenyl-1H-pyrazole 
• 54864-81-2 3-(heptafluoropropyl)-1-methyl-5-phenyl-1H-pyrazole 
• 83389-13-3 Diethyl-(3-heptafluoropropyl-5-phenyl-pyrazol-1-ylmethyl)-amine 

Relevant academic research and scientific papers

Oxygenative perfluoroalkylation of olefinic compounds using perfluoroalkyl iodide in the presence of oxygen

Reactions of perfluoroalkyl iodides with styrene and its derivatives were investigated under radical conditions in the presence of oxygen. The photochemical reaction of styrene with CF3(CF2)5I in the presence of tributyltin hydride or tris(trimethylsilyl)silane under an oxygen atmosphere afforded the corresponding perfluoroalkylated alcohols in moderate yields together with CF3(CF2)5H. However, the photochemical reactions of styrene and its derivatives with CF3(CF2)nI (n = 3, 5) in the presence of hexabutylditin under oxygen produced the perfluoroalkylated alcohols in good yields. Furthermore, the reactions of styrenes with CF3(CF2)nI (n = 3, 5, 9) and Na2S2O4 in the presence of a base under air formed the same alcohols in good yields. The alcohols were found to provide a novel type of α-fluoroalkylated styrenes by acidic dehydration. Perfluoroalkylated α,β-unsaturated ketones were synthesized by oxygenative perfluoroalkylations of α-chlorostyrene and its derivatives using CF3(CF2)nI (n = 3, 5) under radical reaction conditions. The ketones were found to be good synthetic building blocks for perfluoroalkylated heterocycles, such as pyrazoles, dihydrodiazepines, pyrimidines, and isoxazoles.

Novel synthesis of perfluoroalkylated heterocyclic compounds from α-chlorostyrenes via perfluoroalkylated α,β-unsaturated ketones

A convenient method for the one-pot synthesis of heterocyclic compounds bearing a perfluoroalkyl group from α-chlorostyrenes via perfluoroalkylated α,β-unsaturated ketones has been developed.

Synthesis of 3-perfluoroalkyl-, including 3-trifluoromethyl-, substituted pyrazoles from perfluoroalkylacetylenes

3-Perfluoroalkylpyrazoles 2 have been prepared in excellent yield by the reactions of perfluoroalkylacetylenes 1 with hydrazine monohydrate under mild conditions. - Keywords: Perfluoroalkylpyrazoles; Synthesis; Perfluoroalkylacetylenes; Hydrazene; Nucleop

Synthese des F-alkylpyrazoles: Identification par RMN de 19F et comparaison avec les homologues hydrocarbones

In this paper, we report the synthesis of forty new pyrazoles substituted by one or more perfluoroalkyl chains.These compounds were obtained by condensation of a hydrazine (substituted or not) on an F-alkyl β-diketone.Unlike hydrocarbon chemistry, a react