548771-68-2 Usage
Uses
Used in Organic Synthesis:
5-Fluoro-2-tetralone is utilized as a key building block in organic synthesis for the production of various pharmaceuticals and biologically active compounds. Its unique structure and reactivity facilitate the creation of diverse molecular structures, contributing to the development of new and innovative chemical entities.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 5-Fluoro-2-tetralone serves as an essential intermediate for the synthesis of pharmaceuticals with potential therapeutic applications. Its unique chemical properties allow for the design and synthesis of novel drug candidates, enhancing the discovery and development of new medications.
Used in Drug Discovery:
5-Fluoro-2-tetralone plays a crucial role in drug discovery, where its unique structure and reactivity are leveraged to create new molecular entities with potential therapeutic benefits. Its contribution to the development of diverse molecular structures aids in the identification of promising drug candidates for further research and development.
Used in Pharmaceutical Industry:
5-Fluoro-2-tetralone is employed as a valuable intermediate in the pharmaceutical industry for the synthesis of a wide range of biologically active compounds. Its unique properties enable the development of innovative drugs with improved efficacy, safety, and selectivity, ultimately contributing to advancements in healthcare and medicine.
Check Digit Verification of cas no
The CAS Registry Mumber 548771-68-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,4,8,7,7 and 1 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 548771-68:
(8*5)+(7*4)+(6*8)+(5*7)+(4*7)+(3*1)+(2*6)+(1*8)=202
202 % 10 = 2
So 548771-68-2 is a valid CAS Registry Number.
InChI:InChI=1/C10H9FO/c11-10-3-1-2-7-6-8(12)4-5-9(7)10/h1-3H,4-6H2
548771-68-2Relevant academic research and scientific papers
Bicyclic amine derivatives and their use as anti-psychotic agents
-
, (2008/06/13)
This invention relates to compounds of formula (I) STR1 which are useful as modulators of D3 receptors, in particular as antipsychotic agents.
Benzoquinazoline inhibitors of thymidylate synthase: Enzyme inhibitory activity and cytotoxicity of some 3-amino- and 3-methylbenzo[f]quinazolin- 1(2H)-ones
Pendergast,Johnson,Dickerson,Dev,Duch,Ferone,Hall,Humphreys,Kelly,Wilson
, p. 2279 - 2291 (2007/10/02)
The synthesis and thymidylate synthase (TS) inhibitory activity of a series of simple benzo[f]-quinazolin-1(2H)-ones are described. Fully aromatic 3-amino compounds with compact lipophilic substituents in the 9-position were found to have I50 values as low as 20 nM on the isolated enzyme, and represent the first examples of potent, folate-based TS inhibitors that completely lack any structural feature corresponding to the (p- aminobenzoyl)glutamate moiety of the cofactor. A number of the compounds also showed moderate growth inhibitory activity against a human colon adenocarcinoma cell line (SW480), with IC50 values as low as 2 μM.
