548783-48-8Relevant academic research and scientific papers
Structural Requirements of HDAC Inhibitors: SAHA Analogues Modified at the C2 Position Display HDAC6/8 Selectivity
Negmeldin, Ahmed T.,Padige, Geetha,Bieliauskas, Anton V.,Pflum, Mary Kay H.
, p. 281 - 286 (2017)
Histone deacetylase (HDAC) proteins are epigenetic regulators that deacetylate protein substrates, leading to subsequent changes in cell function. HDAC proteins are implicated in cancers, and several HDAC inhibitors have been approved by the FDA as antica
