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Pseudo-β-yohimbine is a synthetic chemical compound that is structurally similar to the naturally occurring alkaloid β-yohimbine, which is found in the bark of the Pausinystalia yohimbe tree. It is often used as a research chemical and is not approved for medical use. Pseudo-β-yohimbine is known to act as an α2-adrenergic receptor antagonist, which means it can block the action of certain neurotransmitters in the brain, potentially affecting blood pressure, heart rate, and other physiological functions. Due to its structural similarity to β-yohimbine, it is sometimes used in scientific research to study the effects of α2-adrenergic receptor antagonists. However, it is important to note that pseudo-β-yohimbine is not a controlled substance and its effects and safety profile are not as well understood as those of β-yohimbine.

549-82-6

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549-82-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 549-82-6 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,4 and 9 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 549-82:
(5*5)+(4*4)+(3*9)+(2*8)+(1*2)=86
86 % 10 = 6
So 549-82-6 is a valid CAS Registry Number.

549-82-6Relevant academic research and scientific papers

Total Syntheses of Yohimbe Alkaloids, with Stereoselection for the Normal, Allo, and 3-Epiallo Series, Based on Annelations of 4-Methoxy-1,2-dihydropyridones

Kuehne, Martin E.,Muth, Randy S.

, p. 2701 - 2712 (2007/10/02)

N--2,3-dihydro-4-pyridone (31) was generated in two steps (77percent yield) from tryptamine and N-methyl-4-piperidone methiodide.Its cyclization (90percent yield) and oxidation (91percent yield) provided the tetracyclic analogue 32.O-Methylation and Robinson-type annelation of these vinylogous lactams (the latter in form of its Na-carbamate) furnished the dienones 38 (64percent) and 43 (90percent).Further elaboration by cyclization and/or reduction reactions selectively provided the 15,16-didehydroyohimbinones 7 and 44.Their reductions then led to yohimbinone (52, 20percent overall yield from tryptamine), alloyohimbinone (11, 19percent overall yield), and 3-epi-alloyohimbinone (10, 23percent overall yield), which led to yohimbine (3), β-yohimbine (9), 3-epi-alloyohimbine (53), and 3-epi-17-epi-alloyohimbine (54).

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