54920-78-4

Usage

Uses

Used in Pharmaceutical Industry:
2,4-Dichloro-1,7-naphthyridine is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique chemical structure allows for the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical industry, 2,4-Dichloro-1,7-naphthyridine is utilized as a precursor for the production of agrochemicals, such as herbicides and pesticides, which are essential for crop protection and increased agricultural productivity.
Used in Dye and Pigment Industry:
2,4-Dichloro-1,7-naphthyridine is used as a building block in the synthesis of dyes and pigments, which are crucial for coloring textiles, plastics, and other materials. Its chemical properties contribute to the development of vibrant and stable colorants.
Used in Fine Chemicals Industry:
2,4-Dichloro-1,7-naphthyridine is also employed in the production of other fine chemicals, which are used in various applications such as fragrances, flavorings, and specialty chemicals. Its versatility and reactivity make it an essential component in the synthesis of these high-value products.

Upstream product

• 54920-75-1 ethyl 2,4-dihydroxy-1,7-naphthyridine-3-carboxylate 
• 54920-76-2 [1,7]naphthyridine-2,4-diol 
• 55279-30-6 methyl 3-aminoisonicotinate 

Downstream Products

• 16287-97-1 4-chloro-[1,7]naphthyridine 
• 1353969-30-8 4-[2-(2-fluoro-phenyl)-[1,8]naphthyridin-4-yl]-[1,7]naphthyridine 
• 1353969-35-3 4-[2-(2-fluoro-phenyl)-[1,8]naphthyridin-4-yl]-[1,7]naphthyridin-8-ylamine 
• 1353970-49-6 4-[2-(2-fluoro-phenyl)-[1,8]naphthyridin-4-yl]-[1,7]naphthyridine 7-oxide 

Relevant academic research and scientific papers

ISOQUINOLINE DERIVATIVES AS SIK2 INHIBITORS

Provided are compounds of the Formula I, and salts and solvates thereof: (I) wherein R1, R2, R3, X1, X2, X3 and Z are defined in the specification. The compounds are inhibitors of salt-inducible kinase (SIK), particular SIK2, and are useful in therapy, particularly in the treatment of a proliferative disorder, a benign neoplasm, pathological angiogenesis, an inflammatory disease or condition, a musculoskeletal disease or condition, an autoimmune disease, a haematological disease or condition, a neurological disease or condition, a psychiatric disorder, or a metabolic disorder.

INHIBITORS OF LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE (LMPTP) AND USES THEREOF

Protein tyrosine phosphatases (PTPs) are key regulators of metabolism and insulin signaling. As a negative regulator of insulin signaling, the low molecular weight protein tyrosine phosphatase (LMPTP) is a target for insulin resistance and related conditions. Described herein are compounds capable of modulating the level of activity of low molecular weight protein tyrosine phosphatase (LMPTP) and compositions, and methods of using these compounds and compositions.

2,4-DIARYL - SUBSTITUTED [1,8] NAPHTHYRIDINES AS KINASE INHIBITORS FOR USE AGAINST CANCER

The present invention relates to novel [1,8]naphthyridine derivatives of formula (I) and to the use of such compounds in which the inhibition, regulation and/or modulation of signal transduction by ATP consuming proteins like kinases plays a role, particu

2,4- DIARYL-SUBSTITUTED [1,8] NAPHTHYRIDINES AS KINASE INHIBITORS FOR USE AGAINST CANCER

The present invention relates to novel [1,8]naphthyridine derivatives of formula (I) and to the use of such compounds in which the inhibition, regulation and/or modulation of signal transduction by ATP consuming proteins like kinases playsa role, particularly to inhibitors of TGF-beta receptor kinases, and to the use of such compounds for the treatment of kinase-induced diseases, in particular for the treatment of tumors