16287-97-1

Basic information

• Product Name: 4-Chloro-1,7-naphthyridin...
• Synonyms: 4-Chloro-1,7-naphthyridin...
• CAS NO: 16287-97-1
• Molecular Formula: C₈H₅ClN₂
• Molecular Weight: 165
• Mol File: 16287-97-1.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 4-Chloro-1,7-naphthyridin...(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Chloro-1,7-naphthyridin...(16287-97-1)
• EPA Substance Registry System: 4-Chloro-1,7-naphthyridin...(16287-97-1)

Safety Data

• Hazardous Substances Data: 16287-97-1(Hazardous Substances Data)

Usage

Uses

4-Chloro-1,7-naphthyridine is a naphthyridine derivative for possible treatment of cell proliferative disorder.

Upstream product

• 1657-32-5 3-aminopyridine-N-oxide 
• 60122-51-2 1,7-naphthyridin-4(1H)-one 
• 952059-56-2 2,2-dimethyl-5-[[(1-oxidopyridin-3-yl)amino]methylidene]-1,3-dioxane-4,6-dione 
• 1018812-88-8 4-hydroxy-7-oxido-1,7-naphthyridine 
• 54920-78-4 2,4-dichloro-[1,7]naphthyridine 
• 54920-76-2 [1,7]naphthyridine-2,4-diol 
• 55279-30-6 methyl 3-aminoisonicotinate 
• 161871-65-4 1-(3-nitropyridin-4-yl)ethanone 
• 1122-54-9 methyl (4-pyridyl) ketone 

Downstream Products

• 1353969-35-3 4-[2-(2-fluoro-phenyl)-[1,8]naphthyridin-4-yl]-[1,7]naphthyridin-8-ylamine 
• 1353970-49-6 4-[2-(2-fluoro-phenyl)-[1,8]naphthyridin-4-yl]-[1,7]naphthyridine 7-oxide 
• 1353969-30-8 4-[2-(2-fluoro-phenyl)-[1,8]naphthyridin-4-yl]-[1,7]naphthyridine 
• 952059-55-1 2-[2-methoxy-4-(1,7-naphthyridin-4-yloxy)phenyl]acetic acid 
• 952059-58-4 tert-butyl 2-[2-methoxy-4-(1,7-naphthyridin-4-yloxy)phenyl]acetate 

Relevant articles and documents

ARYL LINKED IMIDAZOLE AND TRIAZOLE DERIVATIVES AND METHODS OF USE THEREOF FOR IMPROVING THE PHARMACOKINETICS OF A DRUG

The present invention relates to aryl linked imidazole and triazole derivatives, compositions comprising said compounds, alone or in combination with other drugs, and methods of using the compounds for improving the pharmacokinetics of a drug. The compounds of the invention are useful in human and veterinary medicine for inhbiting CYP3A4 and for improving the pharmacokinetics of a therapeutic compound that is metabolized by CYP3A4.

2,4-DIARYL - SUBSTITUTED [1,8] NAPHTHYRIDINES AS KINASE INHIBITORS FOR USE AGAINST CANCER

The present invention relates to novel [1,8]naphthyridine derivatives of formula (I) and to the use of such compounds in which the inhibition, regulation and/or modulation of signal transduction by ATP consuming proteins like kinases plays a role, particu

NAPHTHYRIDINE DERIVATIVES

The invention concerns naphthyridine derivatives of Formula (Ia) or (Ib) or a pharmaceutically-acceptable salt thereof, wherein each of X1, p, R1, G1, G2, q, R2, R3, R4, R5, Ring A, r and R6 has any of the meanings defined hereinbefore in the description; pharmaceutical compositions containing them and their use in the treatment of cell proliferative disorders or disease states associated with angiogenesis and/or vascular permeability.