54930-66-4

Upstream product

• 54856-83-6 3-dimethylamino-2,2-dimethyl-2H-azirine 
• 65-85-0 benzoic acid 

Downstream Products

• 65563-98-6 2-benzoylamino-2-methyl-propionic acid methyl ester 
• 77919-05-2 2-Benzoylamino-2-methyl-propionsaeureaethylester 
• 7563-05-5 4,4-dimethyl-2-phenyl-5-oxazolone 
• 57224-51-8 N-benzoyl-2-methylalanine 
• 81837-94-7 4,4-dimethyl-2-phenyl-1,3-thiazole-5(4H)-thione 
• 54016-23-8 N-(1-Carbamoyl-1-methylethyl)benzamid 

Relevant academic research and scientific papers

2,4-Bis(4-methylphenylthio)-1,3,2λ5,4λ5-dithiadiphosphetane-2,4-dithione: A New Reagent for Thiation of N,N-Disubstituted Amides

As a new reagent for the thiation of amides, the easily accessible 2,4-bis(4-methylphenylthio)-1,3,2λ5,4λ5-dithiadiphosphetane-2,4-dithione (9) shows a remarkable selectivity.This selectivity - the preferred thiation of N,N-disubstituted amides - is complementary to the one of the well known Lawesson reagent.Thiation of diamides of type 2 with 9 leads via cyclization of the corresponding dithiodiamides directly to 1,3-thiazole-5(4H)-thiones 1.

Selektive Umfunktionalisierung der terminalen Amidgruppe offenkettiger Polyamide via 2-Oxazolin-5-one als Zwischenstufen

Treatment of aqueous or alcoholic solutions of diamides of type 2 with HCl leads to the formation of amide-acids and amide-esters of type 3 (Scheme 1 and Table).It has been shown, that 2-oxazolin-5-ones of type 4 are intermediates of this selective transf