549488-76-8

Usage

Uses

Used in Scientific Research:
2-Amino-5-(1-methylethyl)benzonitrile is used as a research chemical for [application reason], contributing to the advancement of knowledge in various scientific fields.
Used in Biological Applications:
2-Amino-5-(1-methylethyl)benzonitrile is used as a reagent in biological studies for [application reason], aiding in the understanding of biological processes and mechanisms.
Used in Chemical Operations:
2-Amino-5-(1-methylethyl)benzonitrile is used as an intermediate in chemical synthesis for [application reason], facilitating the production of various chemical compounds and materials.

InChI:InChI=1/C10H12N2/c1-7(2)8-3-4-10(12)9(5-8)6-11/h3-5,7H,12H2,1-2H3

Upstream product

• 51605-97-1 2-bromo-4-isopropylaniline 
• 544-92-3 copper(I) cyanide 

Downstream Products

• 660861-95-0 5-isopropyl-2-(2-nitrophenylamino)benzonitrile 
• 660861-99-4 2-(5-fluoro-2-nitrophenylamino)-5-isopropylbenzonitrile 
• 612506-02-2 2-(4-fluoro-2-nitrophenylamino)-5-isopropylbenzonitrile 

Relevant academic research and scientific papers

PIPERAZINE SUBSTITUTED ARYL BENZODIAZEPINES

Described herein are compounds of formula (I) wherein: is an optionally benzo-fused five or six member aromatic ring having zero to three hetero atoms independently selected from N, S, and O; Alk is (C1-4) alkylene or hydroxy substituted (C1-4) alkylene; X is oxygen or sulfur; R1 is hydrogen, (C1-6) fluoroalkyl, (C3-6) cycloalkyl, or (C1-4) alkyl, wherein the (C1-4) alkyl is unsubstituted or substituted with hydroxy, methoxy, ethoxy, OCH2CH2OH, or -CN; R2 is H, halogen, (C1-6) fluoroalkyl, (C1-6) cycloalkyl, OR4, SR4, N02, CN, COR4, C(O)OR4, CONR5R6 , NR5R6, S02NR5R6, NR5COR4, NR5SO2R4, optionally substituted aromatic, or (C1-6) alkyl, wherein (C1-6) alkyl is unsubstituted or substituted with a hydroxy group; R3 is hydrogen, (C1-6) fluoroalkyl, (C2-6) alkenyl, Ar, (C1-4)alkyl-Ar, or (C1-4) alkyl wherein (C1-4) alkyl is unsubsituted or substituted with a phenyl; R4 is hydrogen, (C1-6 alkyl, (C1-6) fluoroalkyl, or optionally substituted aromatic; R5 and R6 are independently hydrogen, (C1-6) alkyl, or optionally substituted aromatic, R7 is hydrogen, (C1-6) alkyl, (C1-6) fluoroalkyl, or optionally substituted aromatic; R8 and R9 are independently hydrogen, (C1-6) alkyl, or optionally substituted aromatic; Ar is optionally substituted phenyl, napthyl, monocyclic heteroaromatic or bicyclic heteroaromatic; Z1 and Z2 are independently selected from hydrogen, halogen, (C1-6) alkyl, (C1-6) fluoroalkyl, OR7, SR7, NO2, CN, COR7, CONR8R9, NR8R9, and optionally substituted aromatic; and all salts, solvates, optical and geometric isomers, and crystalline forms thereof. Also, described are the use of the compounds of formula (I) as antagonists of the dopamine D2 receptor and as agents for the treament of psychosis and bipolar disorders, and pharmaceutical formulations of the compounds of formula (I).