54978-55-1

Usage

Uses

Used in Dye and Pigment Production:
Phenyl 1,4-dihydroxy-2-naphthoate is used as a key intermediate in the production of dyes, pigments, and fluorescent materials for its ability to form stable complexes with metal ions. This property allows for the creation of vibrant and long-lasting colorants used in various industries.
Used in Pharmaceutical Development:
Phenyl 1,4-dihydroxy-2-naphthoate is used as a potential pharmaceutical candidate due to its antioxidant properties. It has been studied for its potential applications in the development of new drugs, particularly in the area of materials science where its unique chemical structure may offer novel therapeutic benefits.
Used in Materials Science:
In the field of materials science, Phenyl 1,4-dihydroxy-2-naphthoate is used as a component in the development of new materials with specific properties. Its ability to form stable complexes with metal ions can contribute to the creation of materials with enhanced stability and performance.
Safety Precautions:
It is important to handle and use Phenyl 1,4-dihydroxy-2-naphthoate with caution, as it can be harmful if ingested or inhaled and may cause skin and eye irritation upon contact. Proper safety measures should be taken during its production, use, and disposal to minimize potential health risks.

InChI:InChI=1/C17H12O4/c18-15-10-14(16(19)13-9-5-4-8-12(13)15)17(20)21-11-6-2-1-3-7-11/h1-10,18-19H

Upstream product

• 31519-22-9 1,4-dihydroxy-2-naphthoic acid 
• 108-95-2 phenol 
• 101-02-0 triphenyl phosphite 

Downstream Products

• 1220707-81-2 phenyl 1,4-bis(trifluoromethylsulfonyloxy)-2-naphthoate 
• 1220707-82-3 phenyl 1,4-bis(3-fluorophenyl)-2-naphthoate 
• 1220707-83-4 phenyl 1,4-bis[4-(trifluoromethyl)phenyl]-2-naphthoate 
• 1220707-84-5 phenyl 1,4-bis(p-tolyl)-2-naphthoate 
• 1220707-85-6 phenyl 1,4-bis(3-methoxyphenyl)-2-naphthoate 
• 1220707-86-7 phenyl 1,4-bis(3-ethoxyphenyl)-2-naphthoate 
• 1220707-87-8 phenyl 1-(2-ethoxyphenyl)-4-(trifluoromethylsulfonyloxy)-2-naphthoate 
• 1220707-88-9 phenyl 1-(2,4-dimethoxyphenyl)-4-(trifluoromethylsulfonyloxy)-2-naphthoate 
• 1220707-89-0 phenyl 1-(2,6-dimethoxyphenyl)-4-(trifluoromethylsulfonyloxy)-2-naphthoate 
• 1220707-90-3 phenyl 1-(4-chlorophenyl)-4-(trifluoromethylsulfonyloxy)-2-naphthoate 
• 1220707-92-5 phenyl 4-(3,4-dimethoxyphenyl)-1-(4-fluorophenyl)-2-naphthoate 
• 1220707-93-6 phenyl 1-(2,4-dimethoxyphenyl)-4-p-tolyl-2-naphthoate 
• 1220707-94-7 phenyl 4-(3,4-dimethoxyphenyl)-1-(4-(trifluoromethyl)phenyl)-2-naphthoate 
• 1220707-95-8 phenyl 4-(4-methoxyphenyl)-1-(4-vinylphenyl)-2-naphthoate 

Relevant academic research and scientific papers

Re2O7 -catalyzed formal [3 + 2] cycloaddition for diverse naphtho[1,2-b]furan-3-carboxamides and their biological evaluation

Diverse naphtho[1,2-b]furan-3-carboxamide derivatives 12a–12q were synthesized in high yield via the novel Re2O7 -catalyzed formal [3+2] cycloaddition of 1,4-naphthoquinones with β-ketoamides as the key step. This methodology offers several advantages, such as environmentally benign character, the use of a mild catalyst, high yields, and ease of handling. The synthesized compounds were screened for their tyrosinase inhibitory, antioxidant, and antibacterial activities. The results showed that compound 12c exhibited excellent tyrosinase inhibitory activity with an IC50 of 13.48 μg/mL, which is comparable to that of kojic acid (IC50 = 19.45 μg/mL). Compounds 12a, 12b, and 12i displayed moderate antioxidant activities in a DPPH assay. Compound 12m showed good activity against S. aureus (MIC = 16 μg/mL), and compound 12p was found to be active against E. coli (MIC = 16 μg/mL).

Facile synthesis of mollugin by kinetic control and anti-HCV (Hepatitis C Virus) activity of its analogues

Mollugin has been reported to have various biological activities including antineoplastic, antitumor, antiviral against the hepatitis B virus, anti-aging and antimutagenic activities. An effective and concise synthesis of mollugin in two steps including kinetic control from the cheap starting material 1,4-naphthoquinone has been introduced, and mollugin derivatives thus prepared are screened for their inhibition ability against the hepatitis C virus (HCV) and the dihydrobenzochromene structure might be an additional anti-HCV agent as a new leading compound.