54985-57-8

Upstream product

• 107-15-3 ethylenediamine 
• 57133-33-2 (S)-2-Azidocarbonyl-pyrrolidine-1-carboxylic acid benzyl ester 
• 3397-33-9 Z-proline N-hydroxysuccinimide ester 
• 1148-11-4 N-Benzyloxycarbonyl-L-proline 

Downstream Products

• 289480-96-2 (2S,2'S)-N,N'-(ethane-1,2-diyl)bis(1-benzylpyrrolidine-2-carboxamide) 
• 289480-97-3 N,N'-bis{[(S)-N-benzyl-pyrrolidin-2-yl]methyl}ethylenediamine 

Relevant academic research and scientific papers

C2-symmetric bisprolinamide as a highly efficient catalyst for direct aldol reaction

(Chemical Equation Presented) The catalytic activity of the prolinamide-type catalysts may be improved by introducing additional prolinamide moiety into the catalyst, while the enantioselectivity can still be maintained or further improved. A C2/sub

Copper(II) complexes of bis(amino amide) ligands: Effect of changes in the amino acid residue

A family of ligands derived from bis(amino amides) containing aliphatic spacers has been prepared, and their protonation and stability constants for the formation of Cu2+ complexes have been determined potentiometrically. Important differences

A unique example of a core-modified bis-proline peptide self-assembling into an infinite hydrogen-bonded β-sheet ribbon: Crystal structure of Z-ProNH(CH2)2NHPro-Z

The crystal structure of Z-ProNH(CH2)2NHPro-Z exhibits an extended backbone, with occurrence of both a cis and a trans conformation preceding the two prolyl residues, that self-assembles into an infinite hydrogen-bonded β-sheet ribbo

Rh and Ir complexes containing multidentate, C2-symmetry ligands. Structural and catalytic properties in asymmetric hydrogenation

A comparative investigation of the interaction of Rh(I) and Ir(I) with a series of mixed-donor multidentate, C2-symmetry ligands has been carried out. The complexes have been prepared by the reaction of [MCl(cod)]2 (cod=1,5-cyclooctadiene) with AgPF6 and further treatment with the ligand. All ligands form 1:1 (metal:ligand) species with the above metal ions although, in a few instances, species of type [M2L2]2+ were also detected. The structures of these complexes were elucidated by analytical and spectroscopic data (elemental analysis, mass spectroscopy, IR, 1H- and 13C-NMR). Complexes were tested in the asymmetric hydrogenation of prochiral olefins, providing enantioselectivities up to 36%.