55-93-6

Usage

Uses

Used in Chemical Synthesis:
Dimethylmyleran is used as an intermediate in the synthesis of various organic compounds, particularly in the production of pharmaceuticals and agrochemicals. Its unique chemical structure allows for versatile reactions and functional group transformations, making it a valuable building block in organic chemistry.
Used in Pharmaceutical Industry:
Dimethylmyleran is used as a key component in the development of new drugs, owing to its ability to form stable esters and its potential to modulate biological activity. Its presence in drug molecules can enhance solubility, stability, and bioavailability, leading to improved therapeutic efficacy.
Used in Agrochemical Industry:
Dimethylmyleran is employed as a precursor in the synthesis of agrochemicals, such as pesticides and herbicides. Its unique properties enable the development of more effective and environmentally friendly products, contributing to sustainable agriculture practices.
Used in Research and Development:
Dimethylmyleran serves as a valuable research tool in the study of chemical reactions and mechanisms. Its reactivity and stability make it an ideal candidate for probing the behavior of various functional groups and understanding the underlying principles of organic chemistry.

InChI:InChI=1/C8H18O6S2/c1-7(13-15(3,9)10)5-6-8(2)14-16(4,11)12/h7-8H,5-6H2,1-4H3

Upstream product

• 2935-44-6 hexane-2,5-diol 
• 124-63-0 methanesulfonyl chloride 
• 38484-56-9 (+/-)-2,5-hexanediol 

Downstream Products

• 216019-41-9 2R,5R-bis(diphenylphosphino)hexane 

Relevant academic research and scientific papers

Development of effective bidentate diphosphine ligands of ruthenium catalysts toward practical hydrogenation of carboxylic acids

Hydrogenation of carboxylic acids (CAs) to alcohols represents one of the most ideal reduction methods for utilizing abundant CAs as alternative carbon and energy sources. However, systematic studies on the effects of metal-to-ligand relationships on the catalytic activity of metal complex catalysts are scarce. We previously demonstrated a rational methodology for CA hydrogenation, in which CA-derived cationic metal carboxylate [(PP)M(OCOR)]+ (M = Ru and Re; P = one P coordination) served as the catalyst prototype for CA self-induced CA hydrogenation. Herein, we report systematic trial- and-error studies on how we could achieve higher catalytic activity by modifying the structure of bidentate diphosphine (PP) ligands of molecular Ru catalysts. Carbon chains connecting two P atoms as well as Ar groups substituted on the P atoms of PP ligands were intensively varied, and the induction of active Ru catalysts from precatalyst Ru(acac)3 was surveyed extensively. As a result, the activity and durability of the (PP)Ru catalyst substantially increased compared to those of other molecular Ru catalyst systems, including our original Ru catalysts. The results validate our approach for improving the catalyst performance, which would benefit further advancement of CA self-induced CA hydrogenation.

Asymmetric synthesis of trans-2,5-dimethylpyrrolidine

A new synthetic route to (2S,5S)-dimethylpyrrolidine 1, which can also be applied to the synthesis of the (2R,5R)-enantiomer, has been developed. The C2-symmetric pyrrolidine can be obtained enantiomerically pure (e.e. ≥ 97%) in 15% overall yield starting from a mixture of isomers of 2,5-hexanediol, via a short reaction sequence using (S)-α-methylbenzylamine as a chiral auxiliary. The crystal and molecular structure of (S)-2'-phenyl-N-ethyl-(2S,5S)-dimethylpyrrolidine picrate 5, showing an antiparallel stacking of the picrate units, is also reported.