550312-20-4

Basic information

• Product Name: N-(4-methylbenzyl)pentanamide
• Synonyms: N-(4-methylbenzyl)pentanamide
• CAS NO: 550312-20-4
• Molecular Formula: C₁₃H₁₉NO
• Molecular Weight: 205.29606
• Mol File: 550312-20-4.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-(4-methylbenzyl)pentanamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-methylbenzyl)pentanamide(550312-20-4)
• EPA Substance Registry System: N-(4-methylbenzyl)pentanamide(550312-20-4)

Safety Data

• Hazardous Substances Data: 550312-20-4(Hazardous Substances Data)

Upstream product

• 2173-56-0 n-pentyl n-pentanoate 
• 104-84-7 para-methylbenzylamine 

Relevant articles and documents

Synthesis of amides from esters and amines with liberation of H2 under neutral conditions

Efficient synthesis of amides directly from esters and amines is achieved under mild, neutral conditions with the liberation of molecular hydrogen. Both primary and secondary amines can be utilized. This unprecedented, general, environmentally benign reaction is homogeneously catalyzed under neutral conditions by a dearomatized ruthenium-pincer PNN complex and proceeds in toluene under an inert atmosphere with a high turnover number (up to 1000). PNP analogues do not catalyze this transformation, underlining the crucial importance of the amine arm of the pincer ligand. A mechanism is proposed involving metal-ligand cooperation via aromatization-dearomatization of the pyridine moiety and hemilability of the amine arm.