55042-82-5

Usage

Compound type

pyrazole derivative

Substituents

2-chlorophenyl group attached to the 5-position, two phenyl groups attached to the 1 and 3 positions

Usage

organic synthesis and drug discovery research

Potential applications

pharmaceuticals and agrochemicals

Reactivity

influenced by the 2-chlorophenyl and diphenyl groups

Biological activity

may be influenced by the substituents

Research status

ongoing in the scientific community

Upstream product

• 65480-18-4 (3-(2-chlorophenyl)oxiran-2-yl)(phenyl)methanone 
• 100-63-0 phenylhydrazine 
• 1619915-64-8 C₂₀H₁₆ClNO₃ 
• 7245-46-7 1,3-diphenyl-5-(2-chlorophenyl)-2-pyrazoline 

Downstream Products

• 55042-91-6 2-phenylpyrazolo<1,5-f>phenanthridine 
• 75640-15-2 3-bromo-2-phenylpyrazolo<1,5-f>phenanthridine 

Relevant academic research and scientific papers

Photooxidation of 3,5-diaryl-1-phenyl-2-pyrazolines: Experimental and computational studies

Photooxidation of various 2-pyrazolines is studied experimentally and computationally. Experimental results show that the electron-donating/withdrawing substituents increases/decreases the rate of this photoreaction. The proposed light-induced electron-tr

Br?nsted acid-mediated annulations of 1-cyanocyclopropane-1-carboxylates with arylhydrazines: Efficient strategy for the synthesis of 1,3,5-trisubstituted pyrazoles

1-Cyanocyclopropane-1-carboxylates are reacted with arylhydrazines to afford 1,3,5-trisubstituted pyrazoles under the influence of a Br?nsted acid. Formally, this transformation can be regarded as an annulation of three-membered rings with α-carbonyl and

Visible light catalyzed aromatization of 1,3,5-triaryl-2-pyrazolines by platinum(II) polypyridyl complex under oxidant-free condition

With visible light (λ=450 nm) irradiation of a catalytic amount of platinum(II) terpyridyl complex, 1,3,5-triaryl-2-pyrazolines can be smoothly converted to their corresponding pyrazoles and hydrogen in quantitative yields with no use of any oxidant at ro

A convenient and efficient protocol for the synthesis of 5-aryl-1,3-diphenylpyrazole catalyzed by hydrochloric acid under ultrasound irradiation

The synthesis of 5-aryl-1,3-diphenylpyrazole via the reactions of 3-aryl-2,3-epoxy-1-phenyl-1-propanone with phenylhydrazine was carried out in 69-99% yields at room temperature under ultrasound irradiation. This method provides several advantages such as

Solvent-free synthesis of 1, 3-diphenyl-5-arylpyrazole derivatives

The synthesis of 1, 3-diphenyl-5-arylpyrazoles via the reactions of 2, 3-epoxy-1-phenyl-3-aryl-1-propanones with phenylhydrazine was carried out in 48-84% yields at 230 °C under solvent-free condition within 1.5 h. This method provides several advantages