55044-30-9

Upstream product

• 98-86-2 acetophenone 
• 89450-27-1 N-(1,2-Diphenyl-2-methoxy)-propane-N'-tosylhydrazine 
• 106537-21-7 1-(diethoxyphosphoryl)-2-(1-phenylethylidene)hydrazine 
• 100-52-7 benzaldehyde 
• 13466-30-3 (1-phenylethylidene)hydrazine 

Downstream Products

• 56587-83-8 acetophenone azine 
• 587846-99-9 Rh(C₆H₃(CH₂P(CH(CH₃)2)2)2)(NCC₆H₅) 
• 587846-98-8 Rh(C₆H₃(CH₂P(CH(CH₃)2)2)2)(NHCHC₆H₅) 

Relevant academic research and scientific papers

Rhodium(III)-catalyzed coupling of aromatic ketazines or oximes with 2-vinyloxirane via C-H activation

Described herein is a rhodium(III)-catalyzed coupling of aromatic ketazines or oximes with 2-vinyloxirane via directed C-H activation. This reaction proceeds efficiently under mild conditions with a low catalyst loading, especially in conditions with room temperature in the absence of additives for aromatic ketazines. A wide range of substituted substrates is supported and a possible mechanism is proposed according to the experimental results of kinetic isotopic effect, reversibility studies, and catalysis with rhodacycle intermediate c1.

A General Synthesis of Unsymmetrical Azines via N-(Diethoxyphosphinyl)-hydrazones

A new synthesis of unsymmetrical azines utilizing diethyl phosphorohydrazidate as starting material and based on Wadsworth-Emmons type phosphoramidate approach is discribed.