55153-64-5

Basic information

• Product Name: 3-(1H-indol-3-yl)-N-phenyl propionamide
• Synonyms: 3-(1H-indol-3-yl)-N-phenyl propionamide
• CAS NO: 55153-64-5
• Molecular Weight: 264.327
• Mol File: 55153-64-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 3-(1H-indol-3-yl)-N-phenyl propionamide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(1H-indol-3-yl)-N-phenyl propionamide(55153-64-5)
• EPA Substance Registry System: 3-(1H-indol-3-yl)-N-phenyl propionamide(55153-64-5)

Safety Data

• Hazardous Substances Data: 55153-64-5(Hazardous Substances Data)

Upstream product

• 5814-93-7 3-(3-indolyl)-propanamide 
• 62-53-3 aniline 
• 830-96-6 Indole-3-propionic acid 
• 113405-13-3 indole-3-propionic acid chloride 

Relevant articles and documents

Synthesis and antibacterial in vitro activity of novel analogues of nematophin

The synthesis and in vitro antibacterial activity of new derivatives and analogues of nematophin are described. It was shown that the unsubstituted amide NH-group is essential for bioactivity. Alkyl- or aryl-substitution at the 1-position results in a distinct increase of antibacterial activity. Addition of protein (blood or serum) to the culture media reduces the inhibitory activity on bacteria.

Iodide/H2O2 catalyzed intramolecular oxidative amination for the synthesis of 3,20-pyrrolidinyl spirooxindoles

An ammonium iodide/hydrogen peroxide-mediated intramolecular oxidative amination of 3-aminoalkyl-2-oxindoles was achieved, affording the corresponding 3,20-pyrrolidinyl spirooxindoles and their 6- or 7-membered analogous in moderate to high yields. This metal-free procedure features very mild reaction conditions, non-toxicity and easily handled hydrogen peroxide as a clean oxidant.