55154-90-0 Usage
General Description
2-(4-Chloro-phenyl)-acetamidine is a chemical compound with the molecular formula C8H9ClN2. It is a derivative of acetamidine, which is an organic compound used in the synthesis of pharmaceuticals and other organic compounds. This specific derivative contains a 4-chloro-phenyl group attached to the acetamidine moiety. 2-(4-Chloro-phenyl)-acetamidine is used in chemical research and drug development for its potential applications in the treatment of various diseases and conditions. It exhibits interesting pharmacological properties and has been studied for its potential as a therapeutic agent in medical research.
Check Digit Verification of cas no
The CAS Registry Mumber 55154-90-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,5,1,5 and 4 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 55154-90:
(7*5)+(6*5)+(5*1)+(4*5)+(3*4)+(2*9)+(1*0)=120
120 % 10 = 0
So 55154-90-0 is a valid CAS Registry Number.
InChI:InChI=1/C8H9ClN2.ClH/c9-7-3-1-6(2-4-7)5-8(10)11;/h1-4H,5H2,(H3,10,11);1H
55154-90-0Relevant articles and documents
Evolution of anti-HIV drug candidates. Part 1: From α-Anilinophenylacetamide (α-APA) to imidoyl thiourea (ITU)
Ludovici, Donald W.,Kukla, Michael J.,Grous, Philip G.,Krishnan, Suma,Andries, Koen,De Bethune, Marie-Pierre,Azijn, Hilde,Pauwels, Rudi,De Clercq, Erik,Arnold, Edward,Janssen, Paul A.J.
, p. 2225 - 2228 (2007/10/03)
Stemming from work on a previous clinical candidate, loviride, and other α-APA derivatives, a new series of potent non-nucleoside reverse transcriptase inhibitors (NNRTIs) has been synthesized. The ITU analogues, which contain a unique diarylated imidoyl thiourea, are very active in inhibiting both wild-type and clinically important mutant strains of HIV-1.
