552-37-4

Basic information

• Product Name: SODIUM ANTHRANILATE
• Synonyms: Benzoicacid,2-amino-,monosodiumsalt;Natrium-2-aminobenzoat;SODIUM 2-AMINOBENZOATE;SODIUM ANTHRANILATE;SODIUM ANTHRANILATE N-HYDRATE;2-AMINOBENZOIC ACID SODIUM SALT;ANTHRANILIC ACID SODIUM SALT;Anthralinicacidsodiumsalt
• CAS NO: 552-37-4
• Molecular Formula: C₇H₆NO₂*Na
• Molecular Weight: 159.12
• EINECS: 209-010-1
• Product Categories: Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
• Mol File: 552-37-4.mol
• Article Data: 3

Chemical Properties

• Melting Point: <250 °C
• Boiling Point: 311.9°Cat760mmHg
• Flash Point: 142.4°C
• Appearance: /
• Density: 1.315g/cm³
• Vapor Pressure: 0.000234mmHg at 25°C
• Storage Temp.: Hygroscopic, Refrigerator, under inert atmosphere
• Solubility: DMSO (Slightly), Methanol (Slightly)
• Stability: Hygroscopic
• CAS DataBase Reference: SODIUM ANTHRANILATE(CAS DataBase Reference)
• NIST Chemistry Reference: SODIUM ANTHRANILATE(552-37-4)
• EPA Substance Registry System: SODIUM ANTHRANILATE(552-37-4)

Safety Data

• Hazardous Substances Data: 552-37-4(Hazardous Substances Data)

Usage

Uses

2-Aminobenzoic Acid Sodium Salt (cas# 552-37-4) is a useful reagent for the preparation of benzisoxazolones.

InChI:InChI=1/C7H7NO2.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4H,8H2,(H,9,10);/q;+1/p-1

Upstream product

• 136918-14-4 phthalimide 
• 118-92-3 anthranilic acid 

Downstream Products

• 612-42-0 phenylglycine-o-carboxylic acid 
• 118-92-3 anthranilic acid 
• 13164-70-0 2-amino-benzoic acid 2-morpholin-4-yl-ethyl ester 
• 5326-47-6 2-amino-5-iodobenzoic acid 
• 5794-88-7 5-Bromo-2-aminobenzoic acid 
• 609-85-8 2-amino-3,5-dibromobenzoic acid 

Relevant articles and documents

Di- and triorganotin(IV) complexes of 2-aminobenzoic acid with and without triphenylphosphine: Synthesis, spectroscopy, semi-empirical study, and antimicrobial activities

Eight organotin carboxylates have been synthesized in quantitative yield by reaction of NaL (L = 2-aminobenzoate) with the di- and triorganotin chlorides and triphenylphosphine. All the complexes have been characterized by elemental analysis, IR, multinuclear NMR (1H, 13C, and 119Sn), and mass spectrometry. The spectroscopic data indicate 1 : 2/1 : 1 M : L stoichiometry in 1, 3, 5, and 7 and 1 : 2 : 1/1 : 1 : 1 M : L : PPh3 stoichiometry in 2, 4, 6, and 8. FT-IR spectra clearly demonstrate metal attachment with both oxygens of the ligand and bidentate coordination in 1, 3, 5, and 7 while monodentate ligand for 2, 4, 6, and 8. In solid state, 1, 2, 5, and 6 exhibit six coordination whereas 3, 4, 7, and 8 show five coordination. The structural behavior is confirmed by semi-empirical study. NMR data reveal four-coordinate geometry in solution. These complexes were screened for antimicrobial activity invitro. The screening tests show that tributyltin carboxylates are more potent antibacterial and fungicidal agents than corresponding methyl derivatives, and triphenylphosphine enhances the antibacterial and fungicidal activities of these complexes.

Anti-inflammatory and anti-ulcer compounds and process

Disclosed herein are anti-inflammatory and anti-ulcer copper coordination compounds and a process for using them in the treatment of arthritis and gastrointestinal ulcers in animal bodies. The copper coordination compounds utilized are the reaction products of copper salts with: 1. aromatic carboxylic acids or their alkaline earth salts; 2. heterocyclic carboxylic acids or their alkaline earth salts; 3. amino acids or their alkaline earth salts; 4. amines; and 5. suitably substituted steroids. The process disclosed comprises administering to experimental animals, orally or parentrally (subcutaneously), in controlled dosages, the aforementioned copper coordination compounds for the treatment of inflammation (i.e., arthritis) and ulcers of the gastrointestinal tract.