552293-57-9

Upstream product

• 552293-38-6 C₃₂H₂₉F₆N₃O₅ 
• 824-94-2 p-methoxybenzyl chloride 
• 552293-34-2 benzyl (2S)-2-({(1-R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy}methyl)-2-phenyl-3,4-dihydropyridine-1(2h)-carboxylate 
• 552293-37-5 C₃₀H₂₇F₆NO₄ 
• 530441-95-3 (R)-1-(1-(bromomethoxy)ethyl)-3,5-bis(trifluoromethyl)benzene 
• 530441-39-5 C₃₄H₂₉F₆NO₅ 

Downstream Products

• 552293-60-4 C₄₂H₄₁F₆N₃O₇ 

Relevant academic research and scientific papers

And as the antagonist aminopyrrolidine deriv. NK1 aminopiperidine (by machine translation)

A NK 1 antagonist having the formula (I), wherein Ar 1 and Ar 2 are optionally substituted phenyl or heteroaryl, X 1 is an ether, thio or imino linkage, R 4 and R 5 are not both H or alkyl, and the remaining variables are as defined in the specification, useful for treating a number of disorders, including emesis, depression, anxiety and cough. Pharmaceutical compositions. Methods of treatment and combinations with other agents are also disclosed.

BRIDGED RING NK1 ANTAGONISTS

A compound having the general structure shown in Formula (I): or pharmaceutically acceptable salts and/or solvates thereof are useful in treating diseases or conditions mediated by NK1 receptors, for example various physiological disorders, symptoms or di